dbPTM

IFNA7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	IFNA7_HUMAN
UniProt AC	P01567
Protein Name	Interferon alpha-7
Gene Name	IFNA7
Organism	Homo sapiens (Human).
Sequence Length	189
Subcellular Localization	Secreted.
Protein Description	Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase..
Protein Sequence	MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFRFPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTNLKKGLRRKD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	MVVLVLSYKSICSLG HHHHHHHHHHHHCCC	12.47	-
48	Phosphorylation	LAQMGRISPFSCLKD HHHCCCCCCCHHCCC	20.66	29514088
51	Phosphorylation	MGRISPFSCLKDRHE CCCCCCCHHCCCCCC	23.17	29514088
103	Phosphorylation	SSAAWEQSLLEKFST CCHHHHHHHHHHHHH	24.33	24719451
174	Phosphorylation	VRAEIMRSFSFSTNL HHHHHHHHHCCCCCH	14.09	25072903
176	Phosphorylation	AEIMRSFSFSTNLKK HHHHHHHCCCCCHHH	21.38	25072903
178	Phosphorylation	IMRSFSFSTNLKKGL HHHHHCCCCCHHHHH	18.39	25072903
179	Phosphorylation	MRSFSFSTNLKKGLR HHHHCCCCCHHHHHC	42.43	25072903

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of IFNA7_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of IFNA7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of IFNA7_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of IFNA7_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of IFNA7_HUMAN

Related Literatures of Post-Translational Modification