IFNA6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IFNA6_HUMAN
• UniProt AC: P05013
• Protein Name: Interferon alpha-6
• Gene Name: IFNA6
• Organism: Homo sapiens (Human).
• Sequence Length: 189
• Subcellular Localization: Secreted.
• Protein Description: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase..
• Protein Sequence: MALPFALLMALVVLSCKSSCSLDCDLPQTHSLGHRRTMMLLAQMRRISLFSCLKDRHDFRFPQEEFDGNQFQKAEAISVLHEVIQQTFNLFSTKDSSVAWDERLLDKLYTELYQQLNDLEACVMQEVWVGGTPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSSSRNLQERLRRKE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	LMALVVLSCKSSCSL HHHHHHHHCCCCCCC	14.11	18491316
31	Phosphorylation	CDLPQTHSLGHRRTM CCCCCCCCCCHHHHH	39.16	-
37	Phosphorylation	HSLGHRRTMMLLAQM CCCCHHHHHHHHHHH	13.59	-
155	Phosphorylation	QRITLYLTEKKYSPC HHHHHHHCCCCCCCC	32.00	21964256
176	Phosphorylation	AEIMRSFSSSRNLQE HHHHHHHHCCHHHHH	28.75	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IFNA6_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IFNA6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IFNA6_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of IFNA6_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.