IFN17_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IFN17_HUMAN
• UniProt AC: P01571
• Protein Name: Interferon alpha-17
• Gene Name: IFNA17
• Organism: Homo sapiens (Human).
• Sequence Length: 189
• Subcellular Localization: Secreted.
• Protein Description: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase..
• Protein Sequence: MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISPFSCLKDRHDFGLPQEEFDGNQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNNLEACVIQEVGMEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQKILRRKD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
48	Phosphorylation	LAQMGRISPFSCLKD HHHCCCCCCHHHCCC	20.66	29514088
51	Phosphorylation	MGRISPFSCLKDRHD CCCCCCHHHCCCCCC	23.17	29514088
103	Phosphorylation	SSAAWEQSLLEKFST CCHHHHHHHHHHHHH	24.33	24719451
155	Phosphorylation	QRITLYLTEKKYSPC HHHHHHHCCCCCCCC	32.00	21964256

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IFN17_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IFN17_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IFN17_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of IFN17_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.