| UniProt ID | IFI44_HUMAN | |
|---|---|---|
| UniProt AC | Q8TCB0 | |
| Protein Name | Interferon-induced protein 44 | |
| Gene Name | IFI44 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 444 | |
| Subcellular Localization | Cytoplasm . | |
| Protein Description | This protein aggregates to form microtubular structures.. | |
| Protein Sequence | MAVTTRLTWLHEKILQNHFGGKRLSLLYKGSVHGFRNGVLLDRCCNQGPTLTVIYSEDHIIGAYAEESYQEGKYASIILFALQDTKISEWKLGLCTPETLFCCDVTKYNSPTNFQIDGRNRKVIMDLKTMENLGLAQNCTISIQDYEVFRCEDSLDERKIKGVIELRKSLLSALRTYEPYGSLVQQIRILLLGPIGAGKSSFFNSVRSVFQGHVTHQALVGTNTTGISEKYRTYSIRDGKDGKYLPFILCDSLGLSEKEGGLCRDDIFYILNGNIRDRYQFNPMESIKLNHHDYIDSPSLKDRIHCVAFVFDASSIQYFSSQMIVKIKRIRRELVNAGVVHVALLTHVDSMDLITKGDLIEIERCEPVRSKLEEVQRKLGFALSDISVVSNYSSEWELDPVKDVLILSALRRMLWAADDFLEDLPFEQIGNLREEIINCAQGKK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 (in isoform 2) | Phosphorylation | - | 5.61 | 29507054 | |
| 14 (in isoform 2) | Phosphorylation | - | 4.33 | 29507054 | |
| 18 | Ubiquitination | HEKILQNHFGGKRLS HHHHHHHCCCCCEEE | 15.12 | - | |
| 22 | Ubiquitination | LQNHFGGKRLSLLYK HHHCCCCCEEEEEEC | 51.01 | 29967540 | |
| 107 | Ubiquitination | LFCCDVTKYNSPTNF EEEEECCCCCCCCCE | 42.13 | 21963094 | |
| 108 | Phosphorylation | FCCDVTKYNSPTNFQ EEEECCCCCCCCCEE | 16.11 | 30108239 | |
| 110 | Phosphorylation | CDVTKYNSPTNFQID EECCCCCCCCCEEEC | 29.97 | 30108239 | |
| 161 | Ubiquitination | SLDERKIKGVIELRK CCCHHHHHHHHHHHH | 50.60 | 29967540 | |
| 199 | Ubiquitination | LGPIGAGKSSFFNSV HCCCCCCHHHHHHHH | 42.25 | - | |
| 205 | Phosphorylation | GKSSFFNSVRSVFQG CHHHHHHHHHHHHCC | 17.47 | 23186163 | |
| 208 | Phosphorylation | SFFNSVRSVFQGHVT HHHHHHHHHHCCCCC | 25.73 | - | |
| 215 | Phosphorylation | SVFQGHVTHQALVGT HHHCCCCCCEEEECC | 11.55 | - | |
| 225 | Phosphorylation | ALVGTNTTGISEKYR EEECCCCCCCCCEEE | 34.29 | - | |
| 235 | Phosphorylation | SEKYRTYSIRDGKDG CCEEEEEEEEECCCC | 15.55 | 24719451 | |
| 240 | Ubiquitination | TYSIRDGKDGKYLPF EEEEEECCCCCEECE | 68.54 | 30230243 | |
| 269 | Phosphorylation | LCRDDIFYILNGNIR CCCCCEEEEECCCCC | 12.58 | - | |
| 299 | Phosphorylation | HDYIDSPSLKDRIHC CCCCCCCCHHHHEEE | 52.59 | 29507054 | |
| 301 | Ubiquitination | YIDSPSLKDRIHCVA CCCCCCHHHHEEEEE | 49.66 | 21963094 | |
| 371 | Ubiquitination | RCEPVRSKLEEVQRK ECCCHHHHHHHHHHH | 49.72 | 29967540 | |
| 392 | Phosphorylation | DISVVSNYSSEWELD HCEEEECCCCCCCCC | 13.18 | - | |
| 408 | Phosphorylation | VKDVLILSALRRMLW HHHHHHHHHHHHHHH | 20.47 | 23403867 | |
| 443 | Methylation | IINCAQGKK------ HHHHHCCCC------ | 43.14 | 23644510 | |
| 443 | "N6,N6-dimethyllysine" | IINCAQGKK------ HHHHHCCCC------ | 43.14 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of IFI44_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of IFI44_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of IFI44_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of IFI44_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
