IFFO2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IFFO2_HUMAN
• UniProt AC: Q5TF58
• Protein Name: Intermediate filament family orphan 2
• Gene Name: IFFO2
• Organism: Homo sapiens (Human).
• Sequence Length: 517
• Protein Sequence: MVNSLLFGEMALAFGCPPGGGGGGCPGGGGGGGGAGPGPSPVTAALRDDLGSNIHLLKGLNVRFRCFLAKVHELERRNRLLEKQLEQQQSERERRLRYKTFSREQAVQTGPELLRPPAPGGGHGLSSGAAAGANANAVALGGLPPGGGSHPQHYGRLPGTIWSYTQVRRTGGGGVETVQGPGVSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEELAKRMNLQTMVDTLQEAAQEADAIQEEMNEKIERLKAELVVFKGLMSDPMTDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDVSKIFQVVPKKKERKVASDDDISEQDGEVNRFSDDEVGSMNITDEMKRMFNQLRETFDFDDDCDSLTWEENEDTLLLWEDFTNCNPTIDLQGEQEENLGNLIHETESFFKTRDKEYQETIGQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLIKGSADRNSPSPSSVASSDSGSTDEIQDEFEREADVEPMVS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
58	Ubiquitination	GSNIHLLKGLNVRFR CCCCHHCCCCCHHHH	68.65	21890473
70	Ubiquitination	RFRCFLAKVHELERR HHHHHHHHHHHHHHH	46.39	-
83	Ubiquitination	RRNRLLEKQLEQQQS HHHHHHHHHHHHHHH	61.22	21906983
98	Phosphorylation	ERERRLRYKTFSREQ HHHHHHHHHHHCHHH	20.97	26074081
99	Ubiquitination	RERRLRYKTFSREQA HHHHHHHHHHCHHHH	36.34	-
100	Phosphorylation	ERRLRYKTFSREQAV HHHHHHHHHCHHHHH	20.22	26074081
102	Phosphorylation	RLRYKTFSREQAVQT HHHHHHHCHHHHHHH	39.89	26074081
199	Phosphorylation	GVQIDTITPEIRALY CEECCCCCHHHHHHH	19.57	24719451
211	Ubiquitination	ALYNVLAKVKRERDE HHHHHHHHHHHHHHH	44.09	21890473
213	Ubiquitination	YNVLAKVKRERDEYK HHHHHHHHHHHHHHH	48.08	-
286	Ubiquitination	LDTKIQEKAMKVDMD CCHHHHHHHHCCCHH	37.09	27667366
289	Ubiquitination	KIQEKAMKVDMDICR HHHHHHHCCCHHHHH	39.69	-
301	Phosphorylation	ICRRIDITAKLCDVA HHHHCHHHHHHHHHH	17.62	-
303	Ubiquitination	RRIDITAKLCDVAQQ HHCHHHHHHHHHHHH	40.78	-
318	Ubiquitination	RNSEDVSKIFQVVPK CCCCCHHHHHHHCCC	47.60	21906983
325	Ubiquitination	KIFQVVPKKKERKVA HHHHHCCCHHCCCCC	65.94	27667366
330	Ubiquitination	VPKKKERKVASDDDI CCCHHCCCCCCCCCC	43.15	21906983
333	Phosphorylation	KKERKVASDDDISEQ HHCCCCCCCCCCHHC	44.55	28961369
338	Phosphorylation	VASDDDISEQDGEVN CCCCCCCHHCCCCCC	35.88	32142685
348	Phosphorylation	DGEVNRFSDDEVGSM CCCCCCCCCCCCCCC	40.70	32142685
354	Phosphorylation	FSDDEVGSMNITDEM CCCCCCCCCCCHHHH	17.52	28348404
358	Phosphorylation	EVGSMNITDEMKRMF CCCCCCCHHHHHHHH	22.39	26471730
431	Phosphorylation	FKTRDKEYQETIGQI HHHCCHHHHHHHHHH	19.86	27642862
434	Phosphorylation	RDKEYQETIGQIELE CCHHHHHHHHHHHHH	18.19	30622161
444	Phosphorylation	QIELELATAKSDMNR HHHHHHHHHHHHHHH	47.44	30622161
446	Ubiquitination	ELELATAKSDMNRHL HHHHHHHHHHHHHHH	42.51	21890473
447	Phosphorylation	LELATAKSDMNRHLH HHHHHHHHHHHHHHH	39.36	30622161
456	Phosphorylation	MNRHLHEYMEMCSMK HHHHHHHHHHHHHHH	6.39	-
461	Phosphorylation	HEYMEMCSMKRGLDV HHHHHHHHHHCCCCH	26.48	-
463	Ubiquitination	YMEMCSMKRGLDVQM HHHHHHHHCCCCHHH	27.33	-
480	Phosphorylation	CRRLIKGSADRNSPS HHHHHHCCCCCCCCC	23.22	22210691
485	Phosphorylation	KGSADRNSPSPSSVA HCCCCCCCCCHHHHC	27.87	22210691
487	Phosphorylation	SADRNSPSPSSVASS CCCCCCCCHHHHCCC	36.92	22210691
489	Phosphorylation	DRNSPSPSSVASSDS CCCCCCHHHHCCCCC	41.61	27794612
490	Phosphorylation	RNSPSPSSVASSDSG CCCCCHHHHCCCCCC	25.70	27794612
493	Phosphorylation	PSPSSVASSDSGSTD CCHHHHCCCCCCCCH	32.30	27794612
494	Phosphorylation	SPSSVASSDSGSTDE CHHHHCCCCCCCCHH	26.51	27794612
496	Phosphorylation	SSVASSDSGSTDEIQ HHHCCCCCCCCHHHH	36.27	27794612
498	Phosphorylation	VASSDSGSTDEIQDE HCCCCCCCCHHHHHH	36.32	22468782
499	Phosphorylation	ASSDSGSTDEIQDEF CCCCCCCCHHHHHHH	40.97	27794612
517	Phosphorylation	ADVEPMVS------- HCCCCCCC-------	28.40	33259812

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IFFO2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IFFO2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IFFO2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of IFFO2_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.