dbPTM

IFA4_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	IFA4_CAEEL
UniProt AC	P90900
Protein Name	Intermediate filament protein ifa-4
Gene Name	ifa-4
Organism	Caenorhabditis elegans.
Sequence Length	575
Subcellular Localization	Cytoplasm.
Protein Description	Cytoplasmic intermediate filaments provide mechanical strength to cells. Non-essential protein..
Protein Sequence	MSESEYRSSISVRPTFNRTMQSTATYGSTISSGTSRTLKITEIGGSNLTSGMSPFGGHAASAIRESRTREKKEMSELNDRLASYIEKVRFLEAQNRKMEKDLNLLRGKWGHDSTSVKVMYETELRSAKDLIADSDKERAQLEDQIKKLVEELNNYRNKLHEAERGADVTRKELDNVLGRLGALEAEIELLKRRISLMEESIGHLKRENHRMIDSLHHARNAVEQETLNRIDYQNQVQTLLEECDFIRRIHDSEIHDLLAMASRDTTVENREYFKNELSSAIREIRSEYDHVSNTTRTDIESWYKLKVQEIHTQNSRNCLEQNYAREEVKRLRTTLGDMRGKMADLEGRNLLLEKQIEDLNYQMEEDMRSYEQSLNDKDTSINKLRDESKILMVELQMLIDTKQTLDAEIVIYRKMLDGEENRAGLRQLVEQVVKTTSIHQTKEIESLRVLKGETTSHSSYSRSAKGNIAIQEAEPSGKYIVLENISRRDENIGDWKLRRKIAGKREIVFTFPREFTLRAQKSVKIFARGQGVHSPPDSLVYDLEDSFGTGNDVVTTLYNKEGEDRASHSQRASHT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	SEYRSSISVRPTFNR HHCCCCCCCCCCCCC	17.64	30078680
46	Phosphorylation	KITEIGGSNLTSGMS EEEEECCCCCCCCCC	24.37	21082442
49	Phosphorylation	EIGGSNLTSGMSPFG EECCCCCCCCCCCCC	27.73	28854356
50	Phosphorylation	IGGSNLTSGMSPFGG ECCCCCCCCCCCCCH	35.35	19060867
53	Phosphorylation	SNLTSGMSPFGGHAA CCCCCCCCCCCHHHH	22.17	28854356
61	Phosphorylation	PFGGHAASAIRESRT CCCHHHHHHHHHHHH	25.64	21082442
479	Phosphorylation	EAEPSGKYIVLENIS ECCCCCCEEEEECCC	37.19	27067626

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of IFA4_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of IFA4_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of IFA4_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of IFA4_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of IFA4_CAEEL

Related Literatures of Post-Translational Modification