dbPTM

IF62_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	IF62_ARATH
UniProt AC	Q9M060
Protein Name	Eukaryotic translation initiation factor 6-2 {ECO:0000255\|HAMAP-Rule:MF_03132}
Gene Name	EIF6-2 {ECO:0000255\|HAMAP-Rule:MF_03132}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	245
Subcellular Localization	Cytoplasm . Nucleus, nucleolus . Shuttles between cytoplasm and nucleus/nucleolus.
Protein Description	Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis..
Protein Sequence	MATRLQFENNCEVGVFSKLTNAYCLVAIGGSENFYSAFESELADVIPIVKTSIGGTRIIGRLCAGNKNGLLVPHTTTDQELQHLRNSLPDQVVVQRIDERLSALGNCIACNDYVALAHTDLDKETEEIIADVLGVEVFRQTIAGNILVGSYCALSNKGGMVHPHTSVEDLEELSTLLQVPLVAGTVNRGSEVIAAGMTVNDWTSFCGSDTTATELSVIDSIFKLREAQPSSIVDEMRKSLIDTYV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
239	Phosphorylation	IVDEMRKSLIDTYV- HHHHHHHHHHHHCC-	21.86	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of IF62_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of IF62_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of IF62_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of IF62_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of IF62_ARATH

Related Literatures of Post-Translational Modification