IF44L_HUMAN - dbPTM
IF44L_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID IF44L_HUMAN
UniProt AC Q53G44
Protein Name Interferon-induced protein 44-like
Gene Name IFI44L
Organism Homo sapiens (Human).
Sequence Length 452
Subcellular Localization Cytoplasm .
Protein Description Exhibits a low antiviral activity against hepatitis C virus..
Protein Sequence MEVTTRLTWNDENHLRKLLGNVSLSLLYKSSVHGGSIEDMVERCSRQGCTITMAYIDYNMIVAFMLGNYINLHESSTEPNDSLWFSLQKKNDTTEIETLLLNTAPKIIDEQLVCRLSKTDIFIICRDNKIYLDKMITRNLKLRFYGHRQYLECEVFRVEGIKDNLDDIKRIIKAREHRNRLLADIRDYRPYADLVSEIRILLVGPVGSGKSSFFNSVKSIFHGHVTGQAVVGSDITSITERYRIYSVKDGKNGKSLPFMLCDTMGLDGAEGAGLCMDDIPHILKGCMPDRYQFNSRKPITPEHSTFITSPSLKDRIHCVAYVLDINSIDNLYSKMLAKVKQVHKEVLNCGIAYVALLTKVDDCSEVLQDNFLNMSRSMTSQSRVMNVHKMLGIPISNILMVGNYASDLELDPMKDILILSALRQMLRAADDFLEDLPLEETGAIERALQPCI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
219PhosphorylationSFFNSVKSIFHGHVT
HHHHHHHHHHCCCCC
28.4722210691
233PhosphorylationTGQAVVGSDITSITE
CCCEEECCCCCCCCE
17.7722210691
237PhosphorylationVVGSDITSITERYRI
EECCCCCCCCEEEEE
28.0422210691
300PhosphorylationFNSRKPITPEHSTFI
CCCCCCCCCCCCCCC
31.0229083192
304PhosphorylationKPITPEHSTFITSPS
CCCCCCCCCCCCCCC
24.2929083192
305PhosphorylationPITPEHSTFITSPSL
CCCCCCCCCCCCCCH
22.4429083192
308PhosphorylationPEHSTFITSPSLKDR
CCCCCCCCCCCHHHH
30.3220068231
309PhosphorylationEHSTFITSPSLKDRI
CCCCCCCCCCHHHHE
14.0020068231
311PhosphorylationSTFITSPSLKDRIHC
CCCCCCCCHHHHEEE
48.0620068231
321PhosphorylationDRIHCVAYVLDINSI
HHEEEEEEEECHHHH
4.9129759185
332PhosphorylationINSIDNLYSKMLAKV
HHHHHHHHHHHHHHH
16.7029759185
377PhosphorylationNFLNMSRSMTSQSRV
CHHHHCCCCCCHHHH
21.0729978859
379PhosphorylationLNMSRSMTSQSRVMN
HHHCCCCCCHHHHHC
25.5129978859
380PhosphorylationNMSRSMTSQSRVMNV
HHCCCCCCHHHHHCH
19.9529900121
382PhosphorylationSRSMTSQSRVMNVHK
CCCCCCHHHHHCHHH
26.9829978859
420O-linked_GlycosylationMKDILILSALRQMLR
HHHHHHHHHHHHHHH
20.4730620550

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of IF44L_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of IF44L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of IF44L_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of IF44L_HUMAN !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of IF44L_HUMAN

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Related Literatures of Post-Translational Modification

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