IEC3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IEC3_SCHPO
• UniProt AC: O94704
• Protein Name: INO80 complex subunit 3
• Gene Name: iec3
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 168
• Subcellular Localization: Nucleus .
• Protein Description: Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair..
• Protein Sequence: MASVKSFKRKYLKLRKSFDSVVLETEEIEQKIAEISEVYRRILLENAHLNDLLIDMNSTVLPTPPASPPGSPYWEAKPVSHTVFLESPSDVFTLEKPIASTHRWLSKLTALSKSTNSTLSTPKSFHSPLQSRGISPSSAQSSAAVSSSRKQKRKRTSEGPSERRARKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	KYLKLRKSFDSVVLE HHHHHHHHCCEEEEC		25720772
87	Phosphorylation	SHTVFLESPSDVFTL CEEEEECCHHHCEEE		24763107
124	Phosphorylation	STLSTPKSFHSPLQS CCCCCCCCCCCCHHH		21712547
127	Phosphorylation	STPKSFHSPLQSRGI CCCCCCCCCHHHCCC		28889911
131	Phosphorylation	SFHSPLQSRGISPSS CCCCCHHHCCCCHHH		21712547
135	Phosphorylation	PLQSRGISPSSAQSS CHHHCCCCHHHHHHH		28889911
137	Phosphorylation	QSRGISPSSAQSSAA HHCCCCHHHHHHHHH		27738172
157	Phosphorylation	KQKRKRTSEGPSERR HHHHHCCCCCHHHHH		29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IEC3_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IEC3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IEC3_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of IEC3_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.