IDI1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IDI1_MOUSE
• UniProt AC: P58044
• Protein Name: Isopentenyl-diphosphate Delta-isomerase 1
• Gene Name: Idi1
• Organism: Mus musculus (Mouse).
• Sequence Length: 227
• Subcellular Localization: Peroxisome.
• Protein Description: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)..
• Protein Sequence: MPEINTSHLDEKQVQLLAEMCILIDENDNKIGADTKKNCHLNENIDKGLLHRAFSVFLFNTENKLLLQQRSDAKITFPGCFTNSCCSHPLSNPGELEENNAIGVKRAAKRRLKAELGIPLEEVDLNEMDYLTRIYYKAQSDGIWGEHEVDYILFLRKNVTLNPDPNEIKSYCYVSKEEVREILKKAASGEIKLTPWFKIIADTFLFKWWDNLNHLSPFVDHEKIHRL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MPEINTSHLDEKQ --CCCCCHHHCCHHH	24.16	28066266
7	Phosphorylation	-MPEINTSHLDEKQV -CCCCCHHHCCHHHH	19.98	28066266
37	Ubiquitination	KIGADTKKNCHLNEN CCCCCCCCCCCCCCC	67.89	-
47	Acetylation	HLNENIDKGLLHRAF CCCCCCCCCHHHHHH	47.89	22826441
55	Phosphorylation	GLLHRAFSVFLFNTE CHHHHHHEEEEEECC	15.81	29514104
71	Phosphorylation	KLLLQQRSDAKITFP CCCEECCCCCCEECC	37.27	29514104
113	Ubiquitination	RAAKRRLKAELGIPL HHHHHHHHHHHCCCH	37.69	-
157	Ubiquitination	DYILFLRKNVTLNPD CEEEEEECCEECCCC	58.90	27667366
169	Ubiquitination	NPDPNEIKSYCYVSK CCCHHHHHHHEEECH	29.24	-
169	Acetylation	NPDPNEIKSYCYVSK CCCHHHHHHHEEECH	29.24	22826441
170	Phosphorylation	PDPNEIKSYCYVSKE CCHHHHHHHEEECHH	26.54	-
176	Acetylation	KSYCYVSKEEVREIL HHHEEECHHHHHHHH	48.10	21728379
192	Ubiquitination	KAASGEIKLTPWFKI HHHCCCCCCCHHHHH	41.84	-
216	Phosphorylation	WDNLNHLSPFVDHEK HHHCCCCCCCCCHHH	14.56	26745281
223	Ubiquitination	SPFVDHEKIHRL--- CCCCCHHHHHCC---	40.15	-
223	Acetylation	SPFVDHEKIHRL--- CCCCCHHHHHCC---	40.15	22826441

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IDI1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IDI1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IDI1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of IDI1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.