IDH1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: IDH1_ARATH
• UniProt AC: Q8LFC0
• Protein Name: Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial
• Gene Name: IDH1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 367
• Subcellular Localization: Mitochondrion .
• Protein Description: Performs an essential role in the oxidative function of the citric acid cycle..
• Protein Sequence: MSRRSLTLLKNLARNANGSGIQTRSVTYMPRPGDGAPRAVTLIPGDGIGPLVTNAVEQVMEAMHAPIFFEKYDVHGEMSRVPPEVMESIRKNKVCLKGGLKTPVGGGVSSLNVQLRKELDLFASLVNCFNLPGLPTRHENVDIVVIRENTEGEYAGLEHEVVPGVVESLKVITKFCSERIAKYAFEYAYLNNRKKVTAVHKANIMKLADGLFLESCREVAKKYPSITYNEIIVDNCCMQLVAKPEQFDVMVTPNLYGNLVANTAAGIAGGTGVMPGGNVGADHAVFEQGASAGNVGKDKIVLENKANPVALLLSSAMMLRHLQFPSFADRLETAVKKVIAEGKCRTKDLGGTSTTQEVVDAVIAKLD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
102	Phosphorylation	CLKGGLKTPVGGGVS EEECCCCCCCCCCCH	28.40	29654922
110	Phosphorylation	PVGGGVSSLNVQLRK CCCCCCHHHCHHHHH	22.89	29654922

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of IDH1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of IDH1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of IDH1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
IDH5_ARATH	IDH-V	physical	21798944

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.