dbPTM

ICE2_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ICE2_DROME
UniProt AC	Q8SZZ8
Protein Name	Little elongation complex subunit 2
Gene Name	Ice2
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	684
Subcellular Localization	Nucleus .
Protein Description	Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III..
Protein Sequence	MFSMDSFAMDKDAKLYEGNALFRNQPSYKVFNKSFEHVDDALYTLLNEVEPDVLRMELQETGDLFKSFNRNSALRDPRNNEVPPKPTRDLTTASSLYSFPNPLEQYSELNLKQQAACMRVLLAWQCSQPVDEQDIVVWQATEKKRYNEQQRVQKYIHDHEQGRKEVIYAPMKSLVAVYRKWYELGVKKLQQTYPNDSYMTFSGLPQLPQCRSLNAQTASIEQVELERIVGRVRLLPEVEVRHEALRTLRLRLDRYATRETRAPVQLLREEDKELELEAGNVFVLPLDSLLMLLTTGSYIDLPTEMFLSLRESPNSKHKCMEFQSPFPPRNCGWHTNSLILKLAYGAYISQPGQAKWLDFNINGAVKEVPDEPACDKSSIDLQMVYKPRAIDQQPSDIEDGNCNSALVSWTLRCKGEGDDCNDFQIFSTLSIPAVKDSSGKEPLGCHFIKLENKPDCGCEIMSKYELISAWVQLKLMRAEMGHCTRISLRDFEPMLEEKLTLISLEQQLHDYYNTSMPQLLSNLCEFLKLLDTVPAGDYLLRYSPKYKDKFLLCIVTKEATPQSFQLHQLLTESIPSDQAFLTQSSYLPISPTLCGRLHEELHLLPCAFPAKANGRSVQRRKVVVPIPEPSRQAPVRRQRLKKWSEAQTREFRRRCKVDQKKRARARKTAAANKEKIELEKIMTL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of ICE2_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ICE2_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ICE2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ICE2_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ICE2_DROME

Related Literatures of Post-Translational Modification