ICDHX_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ICDHX_ARATH
• UniProt AC: Q9SLK0
• Protein Name: Peroxisomal isocitrate dehydrogenase [NADP]
• Gene Name: ICDH
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 416
• Subcellular Localization: Peroxisome .
• Protein Description: May be involved in response to oxidative stresses..
• Protein Sequence: MEFEKIKVINPVVEMDGDEMTRVIWKFIKDKLIFPFLELDIKYFDLGLPNRDFTDDKVTIETAEATLKYNVAIKCATITPDEARVREFGLKKMWRSPNGTIRNILNGTVFREPIICRNIPRLVPGWTKPICIGRHAFGDQYRATDLIVNEPGKLKLVFEPSGSSQKTEFEVFNFTGGGVALAMYNTDESIRAFAESSMYTAYQKKWPLYLSTKNTILKIYDGRFKDIFQEVYEANWRSKYEAAGIWYEHRLIDDMVAYAMKSEGGYVWACKNYDGDVQSDFLAQGYGSLGMMTSVLVCPDGKTIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWSRGLAHRAKLDSNAALLSYTEKLEAACMGTVESGKMTKDLALLIHGAKVRRDQYVNTEEFIDAVAWELKRRLLGNNSRL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
212	Phosphorylation	KWPLYLSTKNTILKI HCCEEEECCCEEEEE		22438062
330	Phosphorylation	GGETSTNSIASIFAW CCCCCHHHHHHHHHH		24894044
333	Phosphorylation	TSTNSIASIFAWSRG CCHHHHHHHHHHHHH		24894044
338	Phosphorylation	IASIFAWSRGLAHRA HHHHHHHHHHHHHHH		24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ICDHX_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ICDHX_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ICDHX_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of ICDHX_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.