I5P1_CAEEL - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: I5P1_CAEEL
• UniProt AC: Q17848
• Protein Name: Probable type I inositol 1,4,5-trisphosphate 5-phosphatase
• Gene Name: ipp-5
• Organism: Caenorhabditis elegans.
• Sequence Length: 409
• Protein Sequence: MVQYLLITANVGSLFEPDARLHTSWIKTVADQVESVDPSFFVIHLQETGGKKFTECSQQVPIIINRLSTALPKFDLLRAYVDIDYEAIEYTALGALCFIKRSLWSNVSQFNFHTKKYEQLTSPKEVVTHGLENYPYVVKHKFPKDFWPSIKWGRKGYMQTRWKIENKVFDFVNAHLFHDESNLALIHENPQLYSQNRKRALDFVLAELSSKENGCTPLLFVFGDLNFRLDSRSFLNRLTERTAQHPVADQEQMGSLADGLQASAANLQVITHPSENLRRTVSAIEFRRESDSDDSQNSCVLRIEKKKFDYFNHKKLLDDWRSYRDDDKETENFQSMFEMHINFPPTYPWSEDPENSETLMKTRAPAWCDRVLMNKNAYSLVEEGEPQYRSFGMETCTGDHKPVMLTFNI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
255	Phosphorylation	ADQEQMGSLADGLQA CCHHHHHHHHHHHHH	18.29	21082442
282	Phosphorylation	ENLRRTVSAIEFRRE HHHHHHHHHHEEECC	23.94	22923814
290	Phosphorylation	AIEFRRESDSDDSQN HHEEECCCCCCCCCC	40.37	28854356
292	Phosphorylation	EFRRESDSDDSQNSC EEECCCCCCCCCCEE	53.23	30078680
295	Phosphorylation	RESDSDDSQNSCVLR CCCCCCCCCCEEEEE	35.93	30078680
298	Phosphorylation	DSDDSQNSCVLRIEK CCCCCCCEEEEEEEE	9.66	30078680

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of I5P1_CAEEL !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of I5P1_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of I5P1_CAEEL !!

Protein-Protein Interaction

Oops, there are no PPI records of I5P1_CAEEL !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.