dbPTM

HXA3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HXA3_MOUSE
UniProt AC	P02831
Protein Name	Homeobox protein Hox-A3
Gene Name	Hoxa3
Organism	Mus musculus (Mouse).
Sequence Length	443
Subcellular Localization	Nucleus.
Protein Description	Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds 5' to its own homeobox..
Protein Sequence	MQKATYYDSSAIYGGYPYQAANGFAYNASQQPYAPSAALGTDGVEYHRPACSLQSPASAGGHPKTHELSEACLRTLSGPPSQPPGLGEPPLPPPPPQAAPPAPQPPQPPPQPPAPTPAAPPPPSSVSPPQSANSNPTPASTAKSPLLNSPTVGKQIFPWMKESRQNTKQKTSGSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGAYGLPPASYPAPLPSCAPPPPPQKRYTAAGSGAGGTPDYDPHAHGLQGNGSYGTPHLQGSPVFVGGSYVEPMSNSGPLFGLTHLPHTTSAAMDYGGTGPLGSGHHHGPGPGEPHPTYTDLTAHHPSQGRIQEAPKLTHL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
144	Phosphorylation	TPASTAKSPLLNSPT CCCCCCCCCCCCCCC	20.51	25777480
149	Phosphorylation	AKSPLLNSPTVGKQI CCCCCCCCCCCHHHH	23.16	26824392
151	Phosphorylation	SPLLNSPTVGKQIFP CCCCCCCCCHHHHHH	41.53	25777480
264	Phosphorylation	LTSSGGQSPSRSPVP CCCCCCCCCCCCCCC	28.28	26824392

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HXA3_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HXA3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HXA3_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of HXA3_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HXA3_MOUSE

Related Literatures of Post-Translational Modification