dbPTM

HUTH1_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HUTH1_CAEEL
UniProt AC	Q20502
Protein Name	Histidine ammonia-lyase {ECO:0000312\|WormBase:F47B10.2}
Gene Name	haly-1 {ECO:0000312\|WormBase:F47B10.2}
Organism	Caenorhabditis elegans.
Sequence Length	677
Subcellular Localization
Protein Description
Protein Sequence	MRLQVQIGTECVVVPCKPDDTIHAVAKKSVEKLRRLRPKLPLADDYFEVRRTVGNSLLDPEDLVSDVLKDSDFIIVAASVEETEDAKEAKKQEEIDNARAEIEKIDNRRRKVSFADSLAPMVLAPPTKLLILDGNSLLPEDLVRCEKGECAIQLSMESEDRIRKARTFLEKIASEHRAVYGVTTGFGTFSNVTIPPEKLKKLQLNLIRSHATGYGEPLAPNRARMLLALRINILAKGHSGISVENIKKMIAAFNAFCVSYVPQQGTVGCSGDLCPLAHLALGLLGEGKMWSPTTGWQPADVVLKKNNLEPLELGPKEGLALINGTQMVTALGAYTLERAHNIARQADVIAALSLDVLKGTTRAYDPDIHRIRPHRGQNLSALRLRALLHSEANPSQIAESHRNCTKVQDAYTLRCVPQVHGVVHDTIEFVREIITTEMNSATDNPLVFADREEIISGGNFHGEYPAKALDFLAIAVAELAQMSERRLERLVNKELSGLPTFLTPDGGLNSGFMTVQLCAASLVSENKVLCHPSSVDSIPTSCNQEDHVSMGGFAARKALTVVEHVEAVLAMELLAACQGIEFLKPLISTAPLHKIYQLVRSVAPPLNEDRYMKPEIDAVLEMIRENRIWEAVLPHLETLEAMEELDPDALRQFTKTPTGIVQDRSMIPISDDEESIE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
113	Phosphorylation	DNRRRKVSFADSLAP HHCCCCCCHHHHCHH	28854356
117	Phosphorylation	RKVSFADSLAPMVLA CCCCHHHHCHHHHCC	28854356
270	"2,3-didehydroalanine (Ser)"	QQGTVGCSGDLCPLA CCCCCCCCCCCHHHH	-
270	Other	QQGTVGCSGDLCPLA CCCCCCCCCCCHHHH	-
656	Phosphorylation	ALRQFTKTPTGIVQD HHHHHCCCCCCCCCC	28854356
658	Phosphorylation	RQFTKTPTGIVQDRS HHHCCCCCCCCCCCC	19530675
665	Phosphorylation	TGIVQDRSMIPISDD CCCCCCCCCCCCCCC	19530675
670	Phosphorylation	DRSMIPISDDEESIE CCCCCCCCCCHHHCC	28854356
675	Phosphorylation	PISDDEESIE----- CCCCCHHHCC-----	30078680

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HUTH1_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HUTH1_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HUTH1_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of HUTH1_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HUTH1_CAEEL

Related Literatures of Post-Translational Modification