HSPB1_CHICK - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HSPB1_CHICK
• UniProt AC: Q00649
• Protein Name: Heat shock protein beta-1
• Gene Name: HSPB1
• Organism: Gallus gallus (Chicken).
• Sequence Length: 193
• Subcellular Localization: Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle .
• Protein Description: Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Plays a role in stress resistance and actin organization..
• Protein Sequence: MAERRVPFTFLTSPSWEPFRDWYHGSRLFDQSFGMPHIPEDWYKWPSGSAWPGYFRLLPSESALLPAPGSPYGRALSELSSGISEIRQSADSWKVTLDVNHFAPEELVVKTKDNIVEITGKHEEKQDEHGFISRCFTRKYTLPPGVEATAVRSSLSPDGMLTVEAPLPKPAIQSSEITIPVTVEAKKEEPAKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	FTFLTSPSWEPFRDW EEEECCCCCCCCHHH	43.78	-
70	Phosphorylation	ALLPAPGSPYGRALS CCCCCCCCHHHHHHH	17.56	23106611
77	Phosphorylation	SPYGRALSELSSGIS CHHHHHHHHHHHCHH	35.19	-
80	Phosphorylation	GRALSELSSGISEIR HHHHHHHHHCHHHHH	23.59	-
81	Phosphorylation	RALSELSSGISEIRQ HHHHHHHHCHHHHHH	53.42	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HSPB1_CHICK !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HSPB1_CHICK !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HSPB1_CHICK !!

Protein-Protein Interaction

Oops, there are no PPI records of HSPB1_CHICK !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.