HSP7E_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HSP7E_ARATH
• UniProt AC: Q9S9N1
• Protein Name: Heat shock 70 kDa protein 5
• Gene Name: HSP70-5
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 646
• Subcellular Localization: Cytoplasm .
• Protein Description: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage (By similarity)..
• Protein Sequence: MATKSEKAIGIDLGTTYSCVGVWMNDRVEIIPNDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFSDPSVQSDILHWPFKVVSGPGEKPMIVVSYKNEEKQFSPEEISSMVLVKMKEVAEAFLGRTVKNAVVTVPAYFNDSQRQATKDAGAISGLNVLRIINEPTAAAIAYGLDKKGTKAGEKNVLIFDLGGGTFDVSLLTIEEGVFEVKATAGDTHLGGEDFDNRLVNHFVAEFRRKHKKDIAGNARALRRLRTACERAKRTLSSTAQTTIEIDSLHEGIDFYATISRARFEEMNMDLFRKCMDPVEKVLKDAKLDKSSVHDVVLVGGSTRIPKIQQLLQDFFNGKELCKSINPDEAVAYGAAVQAAILTGEGSEKVQDLLLLDVAPLSLGLETAGGVMTVLIPRNTTVPCKKEQVFSTYADNQPGVLIQVYEGERARTRDNNLLGTFELKGIPPAPRGVPQINVCFDIDANGILNVSAEDKTAGVKNQITITNDKGRLSKEEIEKMVQDAEKYKAEDEQVKKKVEAKNSLENYAYNMRNTIKDEKLAQKLTQEDKQKIEKAIDETIEWIEGNQLAEVDEFEYKLKELEGICNPIISKMYQGGAAAGGMPTDGDFSSSGAAGGPKIEEVD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
168	Phosphorylation	TKDAGAISGLNVLRI HCCCCCCCCCCHHHH	36.37	23776212
227	Phosphorylation	GVFEVKATAGDTHLG CEEEEEECCCCCCCC	26.00	25561503
231	Phosphorylation	VKATAGDTHLGGEDF EEECCCCCCCCCCCC	20.34	30407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HSP7E_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HSP7E_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HSP7E_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of HSP7E_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.