HSP1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HSP1_HUMAN
• UniProt AC: P04553
• Protein Name: Sperm protamine P1
• Gene Name: PRM1
• Organism: Homo sapiens (Human).
• Sequence Length: 51
• Subcellular Localization: Nucleus. Chromosome.
• Protein Description: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex..
• Protein Sequence: MARYRCCRSQSRSRYYRQRQRSRRRRRRSCQTRRRAMRCCRPRYRPRCRRH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	ARYRCCRSQSRSRYY CCCCCCCCHHHHHHH	20.70	8218377
11	Phosphorylation	YRCCRSQSRSRYYRQ CCCCCCHHHHHHHHH	33.21	8218377
13	Phosphorylation	CCRSQSRSRYYRQRQ CCCCHHHHHHHHHHH	29.86	30622161

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HSP1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HSP1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HSP1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of HSP1_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.