dbPTM

HRD3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HRD3_SCHPO
UniProt AC	Q9USV0
Protein Name	Putative ERAD-associated E3 ubiquitin-protein ligase component
Gene Name	SPBC28F2.08c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	713
Subcellular Localization	Endoplasmic reticulum membrane Single-pass membrane protein.
Protein Description	Component of the endoplasmic reticulum quality control (ERQC) system involved in ubiquitin-dependent degradation of missfolded endoplasmic reticulum proteins..
Protein Sequence	MQLLNFLICLFFIFKRCVFTVIGGEFSYDNIDKKPILVASYPEGSRFNVSASIKTLPDLVTLTFPKLVKDPGYVYEEAEKGDPESQFLIAMLYAMGPDERLGLSFPRNEPLSRIFLELSATQNYTYALLALAYKHLNGLSTPMSVDKGVELYKQVAHQISCLVQPLSHFAPDIAAEYPVDLYDLSRTSSYSVQKKDDIVEYLKDYALRGNNISAHISLATIYQYGTPGKLKDIKLAVKHYLAAIRLVNSGIPDSPSEAIKSIHNNPRHAPTTKETANSLSIAAFRLGCMALHGELGKPDPSLAYAWFEYGVSLNHSSSKAAIAYMYFMGYPVAENTESITKLLENALASNDPLAFAVAGKVSLANGQIDEATVHLIRAVSNGHLESVLHIADIYYGSNNQLSIAYYENFISRVLELFDVKTISFDPLTRHFAHRLSAELGNLMSQILAAKDRDPSTSYLKTVIFPTNEQTHRNARIAMNYYSRAAARNHIHSLIKIGDFYRMGLGTSAKPELAFSYYSQAAAIHPSALAYWRLGWMHEYGVGVPVDFEMAKKNYDNALMHDTRAFLAVTLARLRMRLSSPDSWFSNIYRILGKVTYKFLKLVQYFIINIFDILSPAGPDSQLPPEPPTLQVDRTPQQPDPQETSESLPSPNTEEMGESYNDIRFTYDYIDGRFLETACVTLIVVVVGLVLMRRHQQHRLQERRERIIRRQNRA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
48	N-linked_Glycosylation	YPEGSRFNVSASIKT CCCCCCCEECEECCC	26.23	-
123	N-linked_Glycosylation	LELSATQNYTYALLA HHHHCCCCHHHHHHH	27.10	-
211	N-linked_Glycosylation	DYALRGNNISAHISL HHHHCCCCCCCEEEE	32.20	-
314	N-linked_Glycosylation	FEYGVSLNHSSSKAA HHHCCCCCCCCHHHH	26.03	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HRD3_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HRD3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HRD3_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of HRD3_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HRD3_SCHPO

Related Literatures of Post-Translational Modification