dbPTM

HPS5_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HPS5_DROME
UniProt AC	Q9VHN9
Protein Name	Hermansky-Pudlak syndrome 5 protein homolog
Gene Name	p {ECO:0000303\|PubMed:17156100, ECO:0000303\|PubMed:17632576}
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	826
Subcellular Localization
Protein Description	Has a role in the biogenesis of eye pigment granules. Eye pigment granules are specialized forms of late endosomes or lysosomes. Biogenesis of pigment granules in the eye requires molecular components required for protein delivery to lysosomes..
Protein Sequence	MADAYCLTNFIDFSLSLSLPLKHHNRIKYTCFDISDSYIIFGASSGSLYLFNRNGKFLLLIPNKHGAITSLSISANSKYVAFATQRSLICVYAVNLSAQATPQVIFTHLDQSVQVTCIHWTQDEKQFYYGDSRGQVSLVLLSSFIGHSLLFNMTVHPLLYLDSPIVQIDDFEYLLLVSNCTKCILCNTEYEDYKQIGNRPRDGAFGACFFVSPQESLQPSRIYCARPGSRVWEVDFEGEVIQTHQFKTALATAPARIQRPGSGTDELDANAELLDYQPQNLQFAKVQRLNDDFLLAFTELGLYIFDIRRSAVVLWSNQFERIADCRSSGSEIFVFTQSGALYSVQLQTLQSHAVSLIQQSKLLPCANLLRQHVRYFADKAREDYELKQLNPLKQLLIERQEYELLNDISVIFDAITQCTGSALDTHSSGGSSATTERSLSGGSSSRAPPKGVYVLENAFCDNLKQPLKTGHFKDALLTVTGKFGKNIIKYKFNIFAEEQQQLVRELIPASERSLPFKDIKARYESGSEDQEEEIVRRCKKPAPQVPHISPEEKTLYNLYLIAKSAKFSRTQCVDRYRAVFDEYAAGELVNLLEKLAQVMVEHGDTPDQAQRNCYEMYFDYLDPEMIWEVDDATRDHIAAGFVLLNTSQNAEIVKCEHCSFPLRFDTSCQYHELGAVLLRYFWSRGEQLKCFDVVQSVPALLDVLAKFYLAEQNLTKVVAIVLNYGLPELLADVGKQLSVSAWGRCFEQFVELQRGGRLVCANCECISGVEQEQLGRHFFYNWNCFLNIALDHMSAGDTLALIFKWSSYIPNDAIDREFYSRCLLKG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of HPS5_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HPS5_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HPS5_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HPS5_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
WHITE_DROME	w	genetic	11962627
AP3D_DROME	g	genetic	17156100

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HPS5_DROME

Related Literatures of Post-Translational Modification