dbPTM

HPR1_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HPR1_ARATH
UniProt AC	Q9C9W5
Protein Name	Glycerate dehydrogenase HPR, peroxisomal
Gene Name	HPR
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	386
Subcellular Localization	Peroxisome .
Protein Description	Catalyzes the NADH-dependent reduction of hydroxypyruvate into glycerate in the photorespiratory core cycle. Mediates fatty acid beta-oxidation in germinating seeds when malate dehydrogenase is absent..
Protein Sequence	MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENASPPNASPSIVNSKALGLPVSKL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
97	Nitration	FSNMAVGYNNVDVEA CCCCCCCCCCCCHHH	-
178	Phosphorylation	IGAGRIGSAYARMMV ECCCCHHHHHHHHHH	29654922
198	Nitration	NLIYFDLYQSTRLEK EEEEEECCCHHHHHH	-
228	Phosphorylation	PVTWKRASSMEEVLR CCCEEECCCHHHHHH	25561503
229	Phosphorylation	VTWKRASSMEEVLRE CCEEECCCHHHHHHH	30291188
261	Sulfoxidation	VNKERLAMMKKEAIL CCHHHHHHHHCEEEE	25693801
262	Sulfoxidation	NKERLAMMKKEAILV CHHHHHHHHCEEEEE	25693801
334	Phosphorylation	WTREGMATLAALNVL CCHHHHHHHHHHHHH	22092075
365	Phosphorylation	PFLNENASPPNASPS HHHCCCCCCCCCCHH	30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HPR1_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HPR1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HPR1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of HPR1_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HPR1_ARATH

Related Literatures of Post-Translational Modification