dbPTM

HOMEZ_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HOMEZ_MOUSE
UniProt AC	Q80W88
Protein Name	Homeobox and leucine zipper protein Homez
Gene Name	Homez
Organism	Mus musculus (Mouse).
Sequence Length	542
Subcellular Localization	Nucleus .
Protein Description	May function as a transcriptional regulator..
Protein Sequence	MLGHRLLPSLDFPAVSEGYKPEHDMSPNKDASSLNSSAAGLVCLPPVSEELQLVWTQAIQTSELDGNEHLLQAFSYFPYPSLADIALLCLRHGLQMEKVKTWFMAQRLRCGISWSSEEIEETRARVVYHRDQLLFKSLLSFTQQSVRPPQERPPVLRPEQVALGLSPLAPSEQPTHMKGLKVEPEEPSQVSQLPLNHQNAKEPLMMGSRTFSHQSDCQDLQISGLSKEQAGRGPDQSCGKTASWNHFTAVHQPDKPASVSLLDNSCKEESEPSGIPPSSSTSSPSFQALANGTTATPKPLQPLGCISQSLSPSKKALSPQVEPLWPQRLWNNSEPNSAGPTEYLSPDMQHQRKTKRKTKEQLAILKSFFLQCQWARREDYHKLEQITGLPRPEIIQWFGDTRYALKHGQLKWFRDNAVLGTPSFQDPAIPTPSTRSLKEWAKTPPLPAPPPPPDIRPLEKYWAAHQQLQEADILKLSQASRLSTQQVLDWFDSRLPKPAEVVVCLDEEDEEDEEDELPEDGEEEEEEEEDDDDGDDDVIIWD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
175	Phosphorylation	LAPSEQPTHMKGLKV CCCCCCCCCCCCCCC	34.01	-
307	Phosphorylation	LQPLGCISQSLSPSK CCCCCHHCCCCCCCC	20.14	26643407
309	Phosphorylation	PLGCISQSLSPSKKA CCCHHCCCCCCCCCC	24.83	26643407
311	Phosphorylation	GCISQSLSPSKKALS CHHCCCCCCCCCCCC	32.16	25266776
313	Phosphorylation	ISQSLSPSKKALSPQ HCCCCCCCCCCCCCC	43.33	26643407
318	Phosphorylation	SPSKKALSPQVEPLW CCCCCCCCCCCCCCC	20.39	22942356
345	Phosphorylation	AGPTEYLSPDMQHQR CCCCCCCCHHHHHHH	20.25	-
436	Phosphorylation	IPTPSTRSLKEWAKT CCCCCCCCHHHHHHC	43.83	22324799
443	Phosphorylation	SLKEWAKTPPLPAPP CHHHHHHCCCCCCCC	23.53	27180971

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HOMEZ_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HOMEZ_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HOMEZ_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
GT2D1_HUMAN	GTF2IRD1	physical	26275350

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HOMEZ_MOUSE

Related Literatures of Post-Translational Modification