HNRC3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HNRC3_HUMAN
• UniProt AC: B7ZW38
• Protein Name: Heterogeneous nuclear ribonucleoprotein C-like 3 {ECO:0000312|HGNC:HGNC:51235}
• Gene Name: HNRNPCL3 {ECO:0000312|HGNC:HGNC:51235}
• Organism: Homo sapiens (Human).
• Sequence Length: 293
• Subcellular Localization: Nucleus .
• Protein Sequence: MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MASNVTNKMD -----CCCCCCCCCC		-
25	Phosphorylation	VFIGNLNTLVVKKSD EEEEECCEEEEEHHH		30576142
29	Ubiquitination	NLNTLVVKKSDVEAI ECCEEEEEHHHHHHH		21906983
30	Ubiquitination	LNTLVVKKSDVEAIF CCEEEEEHHHHHHHH		-
31	Phosphorylation	NTLVVKKSDVEAIFS CEEEEEHHHHHHHHH		30266825
38	Phosphorylation	SDVEAIFSKYGKIAG HHHHHHHHHHCCCCC		21712546
39	Acetylation	DVEAIFSKYGKIAGC HHHHHHHHHCCCCCC		22641087
39	Sumoylation	DVEAIFSKYGKIAGC HHHHHHHHHCCCCCC		-
39	Methylation	DVEAIFSKYGKIAGC HHHHHHHHHCCCCCC		22641087
39	Ubiquitination	DVEAIFSKYGKIAGC HHHHHHHHHCCCCCC		21890473
42	Ubiquitination	AIFSKYGKIAGCSVH HHHHHHCCCCCCEEE		-
89	Ubiquitination	INLAAEPKVNRGNAG EEECCCCCCCCCCCC		-
100	Phosphorylation	GNAGVKRSAAEMYGS CCCCCCHHHHHHHCC		22210691
105	Phosphorylation	KRSAAEMYGSSFDLD CHHHHHHHCCCCCCC		18669648
107	Phosphorylation	SAAEMYGSSFDLDYN HHHHHHCCCCCCCCC		23663014
108	Phosphorylation	AAEMYGSSFDLDYNL HHHHHCCCCCCCCCC		23663014
124	Phosphorylation	RDYYGGMYSFPARVP CCCCCCCCCCCCCCC		22210691
125	Phosphorylation	DYYGGMYSFPARVPP CCCCCCCCCCCCCCC		22210691
143	Phosphorylation	IALAVVPSKRQRISG EEEEECCCCCCCCCC		30266825
144	Acetylation	ALAVVPSKRQRISGN EEEECCCCCCCCCCC		30590017
152	Phosphorylation	RQRISGNTSRRGKSG CCCCCCCCCCCCCCC		-
157	Ubiquitination	GNTSRRGKSGFNSKS CCCCCCCCCCCCCCC		-
158	Phosphorylation	NTSRRGKSGFNSKSG CCCCCCCCCCCCCCC		28985074
164	Phosphorylation	KSGFNSKSGKRGSSK CCCCCCCCCCCCCCC		22817900
169	Phosphorylation	SKSGKRGSSKSGKLK CCCCCCCCCCCCCCC		24260401
172	Phosphorylation	GKRGSSKSGKLKGDD CCCCCCCCCCCCHHH		26546556
174	Acetylation	RGSSKSGKLKGDDLQ CCCCCCCCCCHHHHH		1206970549
174	Ubiquitination	RGSSKSGKLKGDDLQ CCCCCCCCCCHHHHH		-
176	Sumoylation	SSKSGKLKGDDLQAI CCCCCCCCHHHHHHH		-
176	Methylation	SSKSGKLKGDDLQAI CCCCCCCCHHHHHHH		-
176	Ubiquitination	SSKSGKLKGDDLQAI CCCCCCCCHHHHHHH		-
191	Ubiquitination	KQELTQIKQKVDSLL HHHHHHHHHHHHHHH		-
193	Ubiquitination	ELTQIKQKVDSLLEN HHHHHHHHHHHHHHH		21890473
196	Phosphorylation	QIKQKVDSLLENLEK HHHHHHHHHHHHHHH		30266825
203	Acetylation	SLLENLEKIEKEHCK HHHHHHHHHHHHHHH		83037465
203	Ubiquitination	SLLENLEKIEKEHCK HHHHHHHHHHHHHHH		21890473
216	Acetylation	CKQGVEVKNAKSEEE HHHCCEECCCCCHHH		12438071
220	Phosphorylation	VEVKNAKSEEEQTSS CEECCCCCHHHCCCC		24719451
229	Phosphorylation	EEQTSSSSKKDKTHV HHCCCCCCCCCCCCE		24719451
240	Phosphorylation	KTHVKMESEGGADDS CCCEEEECCCCCCCC		26714015
247	Phosphorylation	SEGGADDSVEEGDLL CCCCCCCCCCCCCCC		26714015
293	Phosphorylation	RANGQDDS------- HHCCCCCC-------		22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HNRC3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HNRC3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HNRC3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of HNRC3_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.