HMMR_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HMMR_MOUSE
• UniProt AC: Q00547
• Protein Name: Hyaluronan mediated motility receptor
• Gene Name: Hmmr
• Organism: Mus musculus (Mouse).
• Sequence Length: 794
• Subcellular Localization: Cell surface . Cytoplasm .
• Protein Description: Receptor for hyaluronic acid (HA). [PubMed: 1376732 Involved in cell motility]
• Protein Sequence: MSFPKAPLKRFNDPSGCAPSPGAYDVKTSEATKGPVSFQKSQRFKNQRESQQNLNIDKDTTLLASAKKAKKSVSKKDSQKNDKDVKRLEKEIRALLQERGTQDKRIQDMESELEKTEAKLNAAVREKTSLSASNASLEKRLTELTRANELLKAKFSEDGHQKNMRALSLELMKLRNKRETKMRSMMVKQEGMELKLQATQKDLTESKGKIVQLEGKLVSIEKEKIDEKCETEKLLEYIQEISCASDQVEKCKVDIAQLEEDLKEKDREILSLKQSLEENITFSKQIEDLTVKCQLLETERDNLVSKDRERAETLSAEMQILTERLALERQEYEKLQQKELQSQSLLQQEKELSARLQQQLCSFQEEMTSEKNVFKEELKLALAELDAVQQKEEQSERLVKQLEEETKSTAEQLTRLDNLLREKEVELEKHIAAHAQAILIAQEKYNDTAQSLRDVTAQLESVQEKYNDTAQSLRDVTAQLESEQEKYNDTAQSLRDVTAQLESEQEKYNDTAQSLRDVTAQLESVQEKYNDTAQSLRDVTAQLESYKSSTLKEIEDLKLENLTLQEKVAMAEKSVEDVQQQILTAESTNQEYARMVQDLQNRSTLKEEEIKEITSSFLEKITDLKNQLRQQDEDFRKQLEEKGKRTAEKENVMTELTMEINKWRLLYEELYEKTKPFQQQLDAFEAEKQALLNEHGATQEQLNKIRDSYAQLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRSQLVKRKQNELRLQGELDKALGIRHFDPSKAFCHASKENFTPLKEGNPNCC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSFPKAPLK ------CCCCCCCCC	50.70	-
9	Acetylation	SFPKAPLKRFNDPSG CCCCCCCCCCCCCCC	54.61	22902405
20	Phosphorylation	DPSGCAPSPGAYDVK CCCCCCCCCCCCCCC	19.90	25619855
24	Phosphorylation	CAPSPGAYDVKTSEA CCCCCCCCCCCCCCC	27.47	23984901
50	Phosphorylation	RFKNQRESQQNLNID HHCCHHHHHHCCCCC	38.98	26824392
60	Phosphorylation	NLNIDKDTTLLASAK CCCCCHHHHHHHHHH	25.69	25619855
61	Phosphorylation	LNIDKDTTLLASAKK CCCCHHHHHHHHHHH	29.88	25619855
65	Phosphorylation	KDTTLLASAKKAKKS HHHHHHHHHHHHHHH	40.36	25619855
134	N-linked_Glycosylation	KTSLSASNASLEKRL HHHCCCCCCHHHHHH	33.01	-
168	Phosphorylation	QKNMRALSLELMKLR HHHHHHHHHHHHHHH	20.86	24759943
206	Phosphorylation	TQKDLTESKGKIVQL HHHHHHHCCCCEEEE	41.28	22006019
275	Phosphorylation	EILSLKQSLEENITF HHHHHHHHHHHCCCH	35.84	26060331
279	N-linked_Glycosylation	LKQSLEENITFSKQI HHHHHHHCCCHHHHH	29.26	-
281	Phosphorylation	QSLEENITFSKQIED HHHHHCCCHHHHHHH	33.18	26060331
283	Phosphorylation	LEENITFSKQIEDLT HHHCCCHHHHHHHHH	18.27	26060331
446	N-linked_Glycosylation	LIAQEKYNDTAQSLR HHHHHHHCHHHHHHH	51.75	-
466	Phosphorylation	LESVQEKYNDTAQSL HHHHHHHHHHHHHHH	19.95	22871156
467	N-linked_Glycosylation	ESVQEKYNDTAQSLR HHHHHHHHHHHHHHH	51.75	-
477	Phosphorylation	AQSLRDVTAQLESEQ HHHHHHHHHHHHHHH	16.99	22871156
482	Phosphorylation	DVTAQLESEQEKYND HHHHHHHHHHHHHHH	53.85	22871156
487	Phosphorylation	LESEQEKYNDTAQSL HHHHHHHHHHHHHHH	19.95	22871156
488	N-linked_Glycosylation	ESEQEKYNDTAQSLR HHHHHHHHHHHHHHH	51.75	-
498	Phosphorylation	AQSLRDVTAQLESEQ HHHHHHHHHHHHHHH	16.99	22871156
503	Phosphorylation	DVTAQLESEQEKYND HHHHHHHHHHHHHHH	53.85	22871156
509	N-linked_Glycosylation	ESEQEKYNDTAQSLR HHHHHHHHHHHHHHH	51.75	-
530	N-linked_Glycosylation	ESVQEKYNDTAQSLR HHHHHHHHHHHHHHH	51.75	-
561	N-linked_Glycosylation	IEDLKLENLTLQEKV HHHHHHCCCCHHHHH	49.08	-
601	N-linked_Glycosylation	RMVQDLQNRSTLKEE HHHHHHHHCCCCCHH	47.36	-
625	Acetylation	LEKITDLKNQLRQQD HHHHHHHHHHHHHCC	45.52	22902405
784	Phosphorylation	HASKENFTPLKEGNP CCCCCCCCCCCCCCC	39.01	24759943

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HMMR_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HMMR_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HMMR_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of HMMR_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.