HMA3A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HMA3A_ARATH
• UniProt AC: P0CW77
• Protein Name: Putative inactive cadmium/zinc-transporting ATPase HMA3
• Gene Name: HMA3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 542
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MAEGEESKKMNLQTSYFDVVGICCSSEVSIVGNVLRQVDGVKEFSVIVPSRTVIVVHDTFLISPLQIVKALNQARLEASVRPYGETSLKSQWPSPFAIVSGVLLVLSFFKYFYSPLEWLAIVAVVAGVFPILAKAVASVTRFRLDINALTLIAVIATLCMQDFTEAATIVFLFSVADWLESSAAHKASIVMSSLMSLAPRKAVIADTGLEVDVDEVGINTVVSVKAGESIPIDGVVVDGSCDVDEKTLTGESFPVSKQRESTVMAATINLNGYIKVKTTALARDCVVAKMTKLVEEAQKSQTKTQRFIDKCSRYYTPAVVVSAACFAVIPVLLKVQDLSHWFHLALVVLVSGCPCGLILSTPVATFCALTKAATSGFLIKTGDCLETLAKIKIVAFDKTGTITKAEFMVSDFRSLSPSINLHKLLYWVSSIECKSSHPMAAALIDYARSVSVEPKPDIVENFQNFPGEGVYGRIDGQDIYIGNKRIAQRAGCLTDNVPDIEATMKRGKTIGYIYMGAKLTGSFNLLDGCRYGVAQALKELKS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
304	Phosphorylation	AQKSQTKTQRFIDKC HHHHCHHHHHHHHHH	28.50	24894044
449	Phosphorylation	ALIDYARSVSVEPKP HHHHHHHHCCCCCCC	15.57	28011693
451	Phosphorylation	IDYARSVSVEPKPDI HHHHHHCCCCCCCCH	23.24	28011693

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HMA3A_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HMA3A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HMA3A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.