dbPTM

HM20B_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HM20B_MOUSE
UniProt AC	Q9Z104
Protein Name	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
Gene Name	Hmg20b
Organism	Mus musculus (Mouse).
Sequence Length	317
Subcellular Localization	Nucleus . Chromosome. Localized to condensed chromosomes in mitosis in conjunction with BRCA2..
Protein Description	Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters (By similarity)..
Protein Sequence	MSHGPRQPGAATAPAGGKTPGQHGAFVVAVKQERSEGSRAGEKGPQEEEPVKKRGWPKGKKRKKILPNGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKMLGAEWSKLQPAEKQRYLDEAEKEKQQYLKELWAYQQSEAYKVCTEKIQENKIKKEDSSSGLMNTLLNGHKGVDCDGFSTFDVPIFTEEFLDQNKAREAELRRLRKMNVAFEEQNAVLQRHTQSMSSARERLEQELALEERRTLALQQQLQAVRQALTASFASLPVPGTGETPTLGTLDFYMARLHGAIERDPAQHERLIARVKEILARVASEHL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
31	Acetylation	GAFVVAVKQERSEGS CCEEEEEEECCCCCC	36.38	22826441
75	Phosphorylation	NGPKAPVTGYVRFLN CCCCCCCHHHHHHHH	23.03	28059163
160	Phosphorylation	NKIKKEDSSSGLMNT CCCCHHHCCCCHHHH	27.74	-
162	Phosphorylation	IKKEDSSSGLMNTLL CCHHHCCCCHHHHHH	39.64	28494245
167	Phosphorylation	SSSGLMNTLLNGHKG CCCCHHHHHHCCCCC	20.75	28494245
208	Ubiquitination	AELRRLRKMNVAFEE HHHHHHHHCHHHHHH	39.14	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HM20B_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HM20B_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HM20B_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of HM20B_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HM20B_MOUSE

Related Literatures of Post-Translational Modification