HLF_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HLF_MOUSE
• UniProt AC: Q8BW74
• Protein Name: Hepatic leukemia factor
• Gene Name: Hlf
• Organism: Mus musculus (Mouse).
• Sequence Length: 295
• Subcellular Localization: Nucleus .
• Protein Sequence: MEKMSRQLPLNPTFIPPPYGVLRSLLENPLKLPLHPEDAFSKEKDKGKKLDDESSSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASSTAPSVMDLSSRATAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
54	Phosphorylation	GKKLDDESSSPTVPQ CCCCCCCCCCCCCCH	43.01	29899451
146	Phosphorylation	PSPNCMQSPIRPGQL CCCCCCCCCCCCCCC	8.73	23384938
241	Methylation	KNNMAAKRSRDARRL HHCHHHHHHHHHHHH	32.00	16288491
243	Methylation	NMAAKRSRDARRLKE CHHHHHHHHHHHHHH	45.71	16288501

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HLF_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HLF_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HLF_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RORB_MOUSE	Rorb	physical	20211142

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.