dbPTM

HIS8_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HIS8_ARATH
UniProt AC	Q9C5U8
Protein Name	Histidinol dehydrogenase, chloroplastic
Gene Name	HISN8
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	466
Subcellular Localization	Plastid, chloroplast.
Protein Description	Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine..
Protein Sequence	MSLNLSRLSLLSSPRISISTHAPRKGYVCCSMKSYRLSELSSSQVDSLKSRPRIDFSSIFATVNPIIDAVRSNGDNAVKEYTERFDKVQLNKVVEDMSELSVPELDSNVKEAFDVAYDNIYAFHLAQKSTEKSVENMKGVRCKRVSRSIGSVGLYVPGGTAVLPSTALMLAIPAQIAGCKTVVLATPPSKDGSICKEVLYCAKRAGVTHILKAGGAQAIAAMAWGTDSCPKVEKIFGPGNQYVTAAKMILQNSEAMVSIDMPAGPSEVLVIADEHASPVYIAADLLSQAEHGPDSQVVLVVVGDSVDLNAIEEEIAKQCKSLPRGEFASKALSHSFTVFARDMIEAISFSNLYAPEHLIINVKDAEKWEGLIENAGSVFIGPWTPESVGDYASGTNHVLPTYGYARMYSGVSLDSFLKFMTVQSLTEEGLRNLGPYVATMAEIEGLDAHKRAVTLRLKDIEAKQLA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
12	Phosphorylation	LSRLSLLSSPRISIS HHHHHHHCCCCEEEE	25561503
13	Phosphorylation	SRLSLLSSPRISIST HHHHHHCCCCEEEEC	25561503
43	Phosphorylation	RLSELSSSQVDSLKS EHHHCCHHHHHHCCC	30291188
181	Phosphorylation	AQIAGCKTVVLATPP HHHCCCCEEEEECCC	28295753
189	Phosphorylation	VVLATPPSKDGSICK EEEECCCCCCCCHHH	28295753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HIS8_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HIS8_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HIS8_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of HIS8_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HIS8_ARATH

Related Literatures of Post-Translational Modification