dbPTM

HFA6A_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HFA6A_ARATH
UniProt AC	Q1PDN3
Protein Name	Heat stress transcription factor A-6a
Gene Name	HSFA6A
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	282
Subcellular Localization	Nucleus .
Protein Description	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE)..
Protein Sequence	MDYNLPIPLEGLKETPPTAFLTKTYNIVEDSSTNNIVSWSRDNNSFIVWEPETFALICLPRCFKHNNFSSFVRQLNTYGFKKIDTERWEFANEHFLKGERHLLKNIKRRKTSSQTQTQSLEGEIHELRRDRMALEVELVRLRRKQESVKTYLHLMEEKLKVTEVKQEMMMNFLLKKIKKPSFLQSLRKRNLQGIKNREQKQEVISSHGVEDNGKFVKAEPEEYGDDIDDQCGGVFDYGDELHIASMEHQGQGEDEIEMDSEGIWKGFVLSEEEMCDLVEHFI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
24	Phosphorylation	PTAFLTKTYNIVEDS CCEEEEEEEEEEECC	19.30	23660473
25	Phosphorylation	TAFLTKTYNIVEDSS CEEEEEEEEEEECCC	12.40	23660473
31	Phosphorylation	TYNIVEDSSTNNIVS EEEEEECCCCCCEEE	26.09	23660473
32	Phosphorylation	YNIVEDSSTNNIVSW EEEEECCCCCCEEEE	47.69	23660473
33	Phosphorylation	NIVEDSSTNNIVSWS EEEECCCCCCEEEEE	35.92	23660473
38	Phosphorylation	SSTNNIVSWSRDNNS CCCCCEEEEECCCCE	18.61	23660473
40	Phosphorylation	TNNIVSWSRDNNSFI CCCEEEEECCCCEEE	23.42	23660473

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HFA6A_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HFA6A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HFA6A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
VOZ1_ARATH	VOZ1	physical	24313737

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HFA6A_ARATH

Related Literatures of Post-Translational Modification