HDX_HUMAN - dbPTM
HDX_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HDX_HUMAN
UniProt AC Q7Z353
Protein Name Highly divergent homeobox
Gene Name HDX
Organism Homo sapiens (Human).
Sequence Length 690
Subcellular Localization Nucleus .
Protein Description
Protein Sequence MNLRSVFTVEQQRILQRYYENGMTNQSKNCFQLILQCAQETKLDFSVVRTWVGNKRRKMSSKNSESGTATTGTSLSAPDITVRNVVNIARPSSQQSSWTSANNDVIVTGIYSPASSSSRQGTNKHTDTQITEAHKIPIQKTATKNDTEFQLHIPVQRQVAHCKNASLLLGEKTIILSRQTSVLNAGNSVFNHAKKNYGNSSVQASEMTVPQKPSVCHRPCKIEPVGIQRSYKPEHTGPALHNLCGQKPTIRDPYCRTQNLEIREVFSLAVSDYPQRILGGNAPQKPSSAEGNCLSIAMETGDAEDEYAREEELASMRAQIPSYSRFYESGSSLRAENQSTTLPGPGRNMPNSQMVNIRDMSDNVLYQNRNYHLTPRTSLHTASSTMYSNTNPLRSNFSPHFASSNQLRLSQNQNNYQISGNLTVPWITGCSRKRALQDRTQFSDRDLATLKKYWDNGMTSLGSVCREKIEAVATELNVDCEIVRTWIGNRRRKYRLMGIEVPPPRGGPADFSEQPESGSLSALTPGEEAGPEVGEDNDRNDEVSICLSEGSSQEEPNEVVPNDARAHKEEDHHAVTTDNVKIEIIDDEESDMISNSEVEQVNSFLDYKNEEVKFIENELEIQKQKYFKLQTFVRSLILAMKADDKEQQQALLSDLPPELEEMDFNHASLEPDDTSFSVSSLSEKNVSESL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
18PhosphorylationQQRILQRYYENGMTN
HHHHHHHHHHCCCCC		11.3620166139
24PhosphorylationRYYENGMTNQSKNCF
HHHHCCCCCCCCHHH		31.3520166139
27PhosphorylationENGMTNQSKNCFQLI
HCCCCCCCCHHHHHH		28.1020166139
135SumoylationTQITEAHKIPIQKTA
CCHHHHCCCCCCCCC		58.1728112733
140SumoylationAHKIPIQKTATKNDT
HCCCCCCCCCCCCCC		40.6328112733
144SumoylationPIQKTATKNDTEFQL
CCCCCCCCCCCEEEE		50.8128112733
163SumoylationQRQVAHCKNASLLLG
HHHHHHCCCCHHHCC		45.7628112733
172SumoylationASLLLGEKTIILSRQ
CHHHCCCCEEEEECC		43.1328112733
181PhosphorylationIILSRQTSVLNAGNS
EEEECCCHHHHCCCH		19.1028555341
194SumoylationNSVFNHAKKNYGNSS
CHHHHHHHHHCCCCC		33.7228112733
212SumoylationSEMTVPQKPSVCHRP
CCCCCCCCCCCCCCC		32.9428112733
221SumoylationSVCHRPCKIEPVGIQ
CCCCCCCEEECCCCC		53.4328112733
231PhosphorylationPVGIQRSYKPEHTGP
CCCCCCCCCCCCCCH		32.5226657352
232SumoylationVGIQRSYKPEHTGPA
CCCCCCCCCCCCCHH		45.2128112733
236PhosphorylationRSYKPEHTGPALHNL
CCCCCCCCCHHHHHH		43.1026657352
327PhosphorylationIPSYSRFYESGSSLR
CCCHHHHHHCCCCCE		14.2127642862
377PhosphorylationNYHLTPRTSLHTASS
CCCCCCCCCEEECCC		36.5221082442
390PhosphorylationSSTMYSNTNPLRSNF
CCCCCCCCCCCCCCC		32.0721082442
398PhosphorylationNPLRSNFSPHFASSN
CCCCCCCCHHHCCCC		23.0128555341
494PhosphorylationIGNRRRKYRLMGIEV
HCCCCEEEEECEEEC		13.73-
613SumoylationDYKNEEVKFIENELE
CCCCCCEEEHHHHHH		43.8528112733
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HDX_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HDX_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HDX_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of HDX_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HDX_HUMAN

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Related Literatures of Post-Translational Modification

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