HDGR3_MOUSE - dbPTM
HDGR3_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HDGR3_MOUSE
UniProt AC Q9JMG7
Protein Name Hepatoma-derived growth factor-related protein 3
Gene Name Hdgfl3
Organism Mus musculus (Mouse).
Sequence Length 202
Subcellular Localization Nucleus.
Protein Description Enhances DNA synthesis and may play a role in cell proliferation..
Protein Sequence MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQTIQQQSSSETEGEGGNTADASSEEEGDRVEDGKGKRKNEKGGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTADLQKAGEGT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
10UbiquitinationRPRPREYKAGDLVFA
CCCCCCCCCCCEEEE		40.9322790023
10 (in isoform 2)Ubiquitination-40.9322790023
66UbiquitinationPKDLFPYKEYKDKFG
HHHCCCHHHHHHHHC		55.6022790023
66 (in isoform 2)Ubiquitination-55.6022790023
97PhosphorylationNNPGVKFTGYQTIQQ
CCCCCCEEEEEEEEC		29.3025293948
99PhosphorylationPGVKFTGYQTIQQQS
CCCCEEEEEEEECCC		10.2224925903
101PhosphorylationVKFTGYQTIQQQSSS
CCEEEEEEEECCCCC		16.5725293948
106PhosphorylationYQTIQQQSSSETEGE
EEEEECCCCCCCCCC		31.3424925903
107PhosphorylationQTIQQQSSSETEGEG
EEEECCCCCCCCCCC		28.0524925903
108PhosphorylationTIQQQSSSETEGEGG
EEECCCCCCCCCCCC		54.5124925903
110PhosphorylationQQQSSSETEGEGGNT
ECCCCCCCCCCCCCC		51.7624925903
117PhosphorylationTEGEGGNTADASSEE
CCCCCCCCCCCCCHH		29.2324925903
121PhosphorylationGGNTADASSEEEGDR
CCCCCCCCCHHCCCC		38.5424925903
122PhosphorylationGNTADASSEEEGDRV
CCCCCCCCHHCCCCC		51.2324925903
158PhosphorylationSKKSSKQSRKSPGDE
CCCCCCCCCCCCCCC		45.4723684622
161PhosphorylationSSKQSRKSPGDEDDK
CCCCCCCCCCCCCCH		32.7627087446
176UbiquitinationDCKEEENKSSSEGGD
HHHHHHHHCCCCCCC		55.8027667366
177PhosphorylationCKEEENKSSSEGGDA
HHHHHHHCCCCCCCC		51.1625521595
178PhosphorylationKEEENKSSSEGGDAG
HHHHHHCCCCCCCCC		33.7422324799
179PhosphorylationEEENKSSSEGGDAGN
HHHHHCCCCCCCCCC		47.5625521595
188PhosphorylationGGDAGNDTRNTTADL
CCCCCCCCCCCHHHH		29.8029899451
191PhosphorylationAGNDTRNTTADLQKA
CCCCCCCCHHHHHHH		21.7722324799
192PhosphorylationGNDTRNTTADLQKAG
CCCCCCCHHHHHHHC		23.0222324799
197UbiquitinationNTTADLQKAGEGT--
CCHHHHHHHCCCC--		66.70-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HDGR3_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HDGR3_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HDGR3_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of HDGR3_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HDGR3_MOUSE

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry.";
Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.;
J. Proteome Res. 7:5314-5326(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-177; SER-178 ANDSER-179, AND MASS SPECTROMETRY.

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