HBS1L_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HBS1L_MOUSE
• UniProt AC: Q69ZS7
• Protein Name: HBS1-like protein
• Gene Name: Hbs1l
• Organism: Mus musculus (Mouse).
• Sequence Length: 682
• Protein Sequence: MARHRNVRGYNYDEDFEDDDLYGQSVEDDYCISPSTAAQFIYSRRDNPEEEYGYEDLRESSNSLLNHQLSEIDQARLYSCLDHMREVLGDAVPDDILTEAILKHKFDVQKALSVVLEQDGVQPWKEKSERAVCAGQPSKGKSVISRSSQSESEIVPKVAKMTVSGKKQTMGFEVPGLTSEENGLSVRAPHKGPPGDDVSVASPNIPETGTPKSALPPPSLQTSEELGSTPTPVRKSGKLRQQIDVKAELEKRQGGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNVNKRTMHKYEQESKKAGKASFAYAWVLDETGEERERGVTMDVGMTKFETTTKVITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITGKLGHFLKQAGFKESDVAFIPTSGLSGENLTARSQSSDLTTWYKGMCLLEQIDSFKPPQRSIDKPFRLCVSDVFKDQGSGFCVTGKIEAGYIQTGDRLLAMPPNETCTAKGITLHDEPVDWAAAGDHVNLTLVGMDIIKINVGCIFCGPKEPIKACTRFRARILVFNIEVPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKLLTKGQNALVELQTQRPVALELYKDFKELGRFMLRYGGSTVAAGVVTEIKE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
33	Phosphorylation	VEDDYCISPSTAAQF CCCCEEECHHHHHHH	14.83	23649490
35	Phosphorylation	DDYCISPSTAAQFIY CCEEECHHHHHHHHH	24.72	23649490
60	Phosphorylation	GYEDLRESSNSLLNH CHHHHHHHHHHHHHH	28.52	25619855
61	Phosphorylation	YEDLRESSNSLLNHQ HHHHHHHHHHHHHHH	26.19	25619855
63	Phosphorylation	DLRESSNSLLNHQLS HHHHHHHHHHHHHHC	35.86	26824392
70	Phosphorylation	SLLNHQLSEIDQARL HHHHHHHCHHHHHHH	26.40	25619855
103	Ubiquitination	ILTEAILKHKFDVQK HHHHHHHHCCCCHHH	38.34	22790023
113	Phosphorylation	FDVQKALSVVLEQDG CCHHHHHHHHHHCCC	18.29	-
142	Phosphorylation	GQPSKGKSVISRSSQ CCCCCCCCCCCCCCC	33.09	26643407
145	Phosphorylation	SKGKSVISRSSQSES CCCCCCCCCCCCCHH	24.77	25266776
147	Phosphorylation	GKSVISRSSQSESEI CCCCCCCCCCCHHHH	26.41	25521595
148	Phosphorylation	KSVISRSSQSESEIV CCCCCCCCCCHHHHC	36.29	25521595
150	Phosphorylation	VISRSSQSESEIVPK CCCCCCCCHHHHCCE	45.07	25521595
152	Phosphorylation	SRSSQSESEIVPKVA CCCCCCHHHHCCEEE	37.56	27742792
162	Phosphorylation	VPKVAKMTVSGKKQT CCEEEEEEECCCEEE	15.71	26643407
164	Phosphorylation	KVAKMTVSGKKQTMG EEEEEEECCCEEECC	35.41	26643407
199	Phosphorylation	GPPGDDVSVASPNIP CCCCCCCCCCCCCCC	20.96	28066266
202	Phosphorylation	GDDVSVASPNIPETG CCCCCCCCCCCCCCC	19.14	26824392
208	Phosphorylation	ASPNIPETGTPKSAL CCCCCCCCCCCHHHC	40.79	30352176
210	Phosphorylation	PNIPETGTPKSALPP CCCCCCCCCHHHCCC	34.66	25521595
213	Phosphorylation	PETGTPKSALPPPSL CCCCCCHHHCCCCCC	35.92	23527152
219	Phosphorylation	KSALPPPSLQTSEEL HHHCCCCCCCCCHHH	38.59	23984901
222	Phosphorylation	LPPPSLQTSEELGST CCCCCCCCCHHHCCC	43.32	23984901
223	Phosphorylation	PPPSLQTSEELGSTP CCCCCCCCHHHCCCC	18.99	23984901
228	Phosphorylation	QTSEELGSTPTPVRK CCCHHHCCCCCCCCC	43.78	26745281
229	Phosphorylation	TSEELGSTPTPVRKS CCHHHCCCCCCCCCC	29.41	26745281
231	Phosphorylation	EELGSTPTPVRKSGK HHHCCCCCCCCCCCH	34.21	25521595
329	Phosphorylation	VTMDVGMTKFETTTK EECCCCCCCEEECEE	27.01	28576409
422	Ubiquitination	RFQEITGKLGHFLKQ HHHHHHHHHHHHHHH	42.52	22790023
504	Phosphorylation	QGSGFCVTGKIEAGY CCCCEEEECEEEEEE	33.66	25521595
526	Phosphorylation	LAMPPNETCTAKGIT EECCCCCCCCCCCEE	23.07	21189417
528	Phosphorylation	MPPNETCTAKGITLH CCCCCCCCCCCEEEC	38.53	21183079
570	Ubiquitination	GCIFCGPKEPIKACT CEEEECCCCHHHHHH	62.50	22790023
620	Malonylation	RLISVLNKSTGEVTK HHHHHHHHCCCCCCC	45.28	26320211
620	Acetylation	RLISVLNKSTGEVTK HHHHHHHHCCCCCCC	45.28	23806337
667	Phosphorylation	LGRFMLRYGGSTVAA HCHHHHHCCCCEEEE	23.13	30635358
670	Phosphorylation	FMLRYGGSTVAAGVV HHHHCCCCEEEEEEE	18.49	30635358
671	Phosphorylation	MLRYGGSTVAAGVVT HHHCCCCEEEEEEEE	19.89	30635358
678	Phosphorylation	TVAAGVVTEIKE--- EEEEEEEEECCC---	29.59	30635358

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HBS1L_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HBS1L_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HBS1L_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of HBS1L_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.