HBA_BOVIN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HBA_BOVIN
• UniProt AC: P01966
• Protein Name: Hemoglobin subunit alpha
• Gene Name: HBA
• Organism: Bos taurus (Bovine).
• Sequence Length: 142
• Protein Description: Involved in oxygen transport from the lung to the various peripheral tissues..
• Protein Sequence: MVLSAADKGNVKAAWGKVGGHAAEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHGAKVAAALTKAVEHLDDLPGALSELSDLHAHKLRVDPVNFKLLSHSLLVTLASHLPSDFTPAVHASLDKFLANVSTVLTSKYR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MVLSAADKGNV ----CCCCHHHCCCC	15.25	-
8	Succinylation	MVLSAADKGNVKAAW CCCCHHHCCCCCCCC	47.89	-
8	Succinylation	MVLSAADKGNVKAAW CCCCHHHCCCCCCCC	47.89	-
12	Succinylation	AADKGNVKAAWGKVG HHHCCCCCCCCCCCC	36.07	-
12	Succinylation	AADKGNVKAAWGKVG HHHCCCCCCCCCCCC	36.07	-
17	Acetylation	NVKAAWGKVGGHAAE CCCCCCCCCCHHHHH	27.31	-
17	Succinylation	NVKAAWGKVGGHAAE CCCCCCCCCCHHHHH	27.31	-
17	Succinylation	NVKAAWGKVGGHAAE CCCCCCCCCCHHHHH	27.31	-
25	Phosphorylation	VGGHAAEYGAEALER CCHHHHHHHHHHHHH	19.53	-
36	Phosphorylation	ALERMFLSFPTTKTY HHHHHHHHCCCCCCC	20.22	-
41	Succinylation	FLSFPTTKTYFPHFD HHHCCCCCCCCCCCC	43.64	-
41	Succinylation	FLSFPTTKTYFPHFD HHHCCCCCCCCCCCC	43.64	-
50	Phosphorylation	YFPHFDLSHGSAQVK CCCCCCCCCCCEEEC	27.87	-
53	Phosphorylation	HFDLSHGSAQVKGHG CCCCCCCCEEECCHH	15.31	29541418
100	Acetylation	RVDPVNFKLLSHSLL CCCCCCHHHHHHHHH	43.23	-
103	Phosphorylation	PVNFKLLSHSLLVTL CCCHHHHHHHHHHHH	22.82	-
109	Phosphorylation	LSHSLLVTLASHLPS HHHHHHHHHHHCCCC	19.31	-
125	Phosphorylation	FTPAVHASLDKFLAN CCHHHHHHHHHHHHH	23.40	-
135	Phosphorylation	KFLANVSTVLTSKYR HHHHHHHHHHHCCCC	18.43	-
138	Phosphorylation	ANVSTVLTSKYR--- HHHHHHHHCCCC---	20.88	-
139	Phosphorylation	NVSTVLTSKYR---- HHHHHHHCCCC----	24.43	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HBA_BOVIN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HBA_BOVIN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HBA_BOVIN !!

Protein-Protein Interaction

Oops, there are no PPI records of HBA_BOVIN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.