HA10_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HA10_MOUSE
• UniProt AC: P01898
• Protein Name: H-2 class I histocompatibility antigen, Q10 alpha chain
• Gene Name: H2-Q10
• Organism: Mus musculus (Mouse).
• Sequence Length: 325
• Subcellular Localization: Membrane; Single-pass type I membrane protein.
• Protein Description: Involved in the presentation of foreign antigens to the immune system..
• Protein Sequence: MGAMAPRTLLLLLAAALAPTQTQAGSHSMRYFETSVSRPGLGEPRFIIVGYVDDTQFVRFDSDAETPRMEPRAPWMEQEGPEYWERETQRAKGNEQSFHVSLRTLLGYYNQSESGSHTIQWMYGCKVGSDGRFLRGYLQYAYDGRDYIALNEDLKTWTAADVAAIITRRKWEQAGAAEYYRAYLEAECVEWLLRYLELGKETLLRTDPPKTHVTHHPGSEGDVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCHVYHEGLPEPLTLRWEPPPSTDSIMSHIADLLWPSLKLWWYL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
35	Phosphorylation	SMRYFETSVSRPGLG HHEEEEEECCCCCCC	15.76	-
92	Ubiquitination	ERETQRAKGNEQSFH HHHHHHHCCCCHHHE	65.54	-
110	N-linked_Glycosylation	RTLLGYYNQSESGSH HHHHHCCCCCCCCCE	30.34	17330941
170	Ubiquitination	AAIITRRKWEQAGAA HHHHHHHHHHHHCHH	52.36	-
200	Ubiquitination	LRYLELGKETLLRTD HHHHHHCHHHHCCCC	61.21	27667366
210	Ubiquitination	LLRTDPPKTHVTHHP HCCCCCCCCCCCCCC	57.56	-
267	Ubiquitination	AGDGTFQKWASVVVP CCCCCCCEEEEEEEE	40.30	-
280	N-linked_Glycosylation	VPLGKEQNYTCHVYH EECCCCCCEEEEEEE	34.86	17330941

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HA10_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HA10_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HA10_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of HA10_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

N-linked Glycosylation

"Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.";
Bernhard O.K., Kapp E.A., Simpson R.J.;
J. Proteome Res. 6:987-995(2007).
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-110 AND ASN-280, AND MASSSPECTROMETRY.
PubMed: 17330941