H10_BOVIN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: H10_BOVIN
• UniProt AC: Q0IIJ2
• Protein Name: Histone H1.0
• Gene Name: H1F0
• Organism: Bos taurus (Bovine).
• Sequence Length: 194
• Subcellular Localization: Nucleus . Chromosome .
• Protein Description: Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division (By similarity)..
• Protein Sequence: MTENSTSTPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKRSVAFKKTKKEVKKVATPKKAAKPKKAASKAPSKKPKATPVKKAKKKPAATPKKTKKPKTVKAKPVKASKPKKTKPVKPKAKSSAKRTGKKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MTENSTST -------CCCCCCCC	10.80	-
2	Acetylation	------MTENSTSTP ------CCCCCCCCC	43.82	-
42	Citrullination	AIQAEKNRAGSSRQS HHHHHHHCCCCCHHH	51.93	-
42	Citrullination	AIQAEKNRAGSSRQS HHHHHHHCCCCCHHH	51.93	-
104	ADP-ribosylation	KSDEPKRSVAFKKTK CCCCCCCCCCCHHHH	24.75	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of H10_BOVIN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of H10_BOVIN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of H10_BOVIN !!

Protein-Protein Interaction

Oops, there are no PPI records of H10_BOVIN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.