dbPTM

GYP2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GYP2_SCHPO
UniProt AC	O94711
Protein Name	GTPase-activating protein gyp2
Gene Name	gyp2 {ECO:0000312\|EMBL:CAA22549.1}
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	720
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description	Stimulates specifically the GTPase activity of ypt2 and ryh1. Inactivates ryh1 during recycling between the endosome and the Golgi compartments (By similarity)..
Protein Sequence	MNLLKHIFLEDDYDAYEGTLDPASFFRINKQEEIIASTVCEIGWEYSKSFGNAYICTSFLCFHSDDFKTRFTFPLAAVRKLERENSDNDTFTFDLSNFHSQIIHLRFKGTRQQSEFFCDRLVRQLHASLEDASSVGLFLLSLASERVCFSESANSQEIESIDLGLGSQFGYPIASSNTNGLINENNSKSWIQYLKKNGANFNLIQTPNFQKLVQSGIPNNLRADIWETCSGSLFPRWKSKGFYAKNIDSVINNRCEYSEEIEKDLTRSLPDYPAYQSPTGINTLRRILLFYSETNKEVGYCQAMNIVLAALLVYCTEEQAYFLFSQLCEFYIPGYYAKIIHGLLLDLTVFEYVLEHTLPHLYQKIIELDMDLKLITINWFFSLFIKDFRLDYAFRILDCLFVNGPRVLFQVALALFKVNAQGILNATDDSSVMKVFRQCFDHINQGTAADEKMAALGSRSSMCTLPQLFAVAFEYFDFITDSFVSAKRKEFKSSVLYSLRCFTKRSHLRSVYQTTLLSNTDLDLVYDAFINAIGENNICHGDVLEQKIDFNGFERLVDCAAPPLSVIREPLHYQRSKRKLFTRLYIWMKDGDSTETSLTFKRIIHGLERLKADIALHSEILCFQLYDLKRDGTLRTEEVVELSESLILLCCYEGDEKDEERLTVISEFLKSCFSGCQDRRSFQITMEDFQAIVDTTGLHATLEFFLKKLIDGLLGKLNAS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of GYP2_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GYP2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GYP2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GYP2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
YJB1_SCHPO	dbl2	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GYP2_SCHPO

Related Literatures of Post-Translational Modification