GUAD_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GUAD_SCHPO
• UniProt AC: O14057
• Protein Name: Probable guanine deaminase
• Gene Name: SPCC1672.03c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 527
• Protein Description: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia..
• Protein Sequence: MDGHTCDVFVGKLIHTPSLGELEITDATVGVYNGKIVFLEKSMTPKTLEEAKSHHLLKEATIHKLKPLQFMFPGLIDTHIHAPQYPNSGIGIDVPLLQWLEKYTFPLESSLADLEEARQVYKRVVERTLSNGTTFASYFSTLHTPTSALLAEICYSYGQRAYIGKCNMNNLSPDHYCEKSAESSLEATRQLISYMSILDPKREMVTPIITPRFAPSCTEDLLSGCGELAEKHNLPIQTHISENTSEIELVKELFPERKSYADVYDYYKLLTPQTILAHAIHLEDEEIELLTKRSSGISHCPTSNSILASGLANVRKLLDSGINVGLGTDVSGGYAPSILIALRHAAMTSRSLSYVLGDPKVMLDLSELLYLATQGGAEVVSRGDQVGSFAVGKYWDALIVDLSAETHSCVDIFERDTWPVMLSKWVFTSDDRNLAQVWVNGRLVSGFEMKANLKNSTPLTNGVTSSGHQVFKELTQAHLLPRTQCVDTPPSCCGGHCCKEESCRTENCKGAYPANATVTVEEDSGMS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
244	Phosphorylation	QTHISENTSEIELVK EEEECCCCCHHHHHH	24.56	25720772
260	Phosphorylation	LFPERKSYADVYDYY HCCCCCCCHHHHHHH	15.17	25720772
491	Phosphorylation	QCVDTPPSCCGGHCC CCCCCCCCCCCCCCC	24.20	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GUAD_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GUAD_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GUAD_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of GUAD_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.