GTR3_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GTR3_RAT
• UniProt AC: Q07647
• Protein Name: Solute carrier family 2, facilitated glucose transporter member 3
• Gene Name: Slc2a3
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 493
• Subcellular Localization: Cell membrane ; Multi-pass membrane protein .
• Protein Description: Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport..
• Protein Sequence: MGTAKVTPSLVFAVTVATIGSFQFGYNTGVINAPETIIKDFLNYTLEERLEDLPREGLLTTLWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEMLILGRLIIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQVFGLDFILGSEELWPGLLGLTIIPAILQSAALPFCPESPRFLLINRKEEDQATEILQRLWGTPDVIQEIQEMKDESIRMSQEKQVTVLELFKSPSYFQPLLISVVLQLSQQFSGINAVFYYSTGIFQDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDEYEAMSFVCIVAILVYVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGMFFPSAAAYLGAYVFIIFAAFLVFFLIFTSFKVPETKGRTFEDITRAFEGQAHSGKGSAGVELNSMQPVKETPGNA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	N-linked_Glycosylation	TIIKDFLNYTLEERL HHHHHHHCCCHHHHH	27.95	-
217	Acetylation	RFLLINRKEEDQATE CEEEEECCCHHHHHH	62.05	22902405
217	Ubiquitination	RFLLINRKEEDQATE CEEEEECCCHHHHHH	62.05	-
232	Phosphorylation	ILQRLWGTPDVIQEI HHHHHHCCHHHHHHH	12.53	22673903
457	Phosphorylation	VPETKGRTFEDITRA CCCCCCCCHHHHHHH	39.79	23800682
471	Phosphorylation	AFEGQAHSGKGSAGV HHCCCCCCCCCCCCC	45.26	-
475	Phosphorylation	QAHSGKGSAGVELNS CCCCCCCCCCCEECC	25.90	23298284
482	Phosphorylation	SAGVELNSMQPVKET CCCCEECCCCCCCCC	31.27	22673903
487	Ubiquitination	LNSMQPVKETPGNA- ECCCCCCCCCCCCC-	63.65	-
489	Phosphorylation	SMQPVKETPGNA--- CCCCCCCCCCCC---	30.67	22673903

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GTR3_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GTR3_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GTR3_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of GTR3_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.