| UniProt ID | GTR3_MOUSE | |
|---|---|---|
| UniProt AC | P32037 | |
| Protein Name | Solute carrier family 2, facilitated glucose transporter member 3 | |
| Gene Name | Slc2a3 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 493 | |
| Subcellular Localization |
Cell membrane Multi-pass membrane protein . |
|
| Protein Description | Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport.. | |
| Protein Sequence | MGTTKVTPSLVFAVTVATIGSFQFGYNTGVINAPETILKDFLNYTLEERLEDLPSEGLLTALWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLLAIIAGCLMGFAKIAESVEMLILGRLLIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQIFGLDFILGSEELWPGLLGLTIIPAILQSAALPFCPESPRFLLINKKEEDQATEILQRLWGTSDVVQEIQEMKDESVRMSQEKQVTVLELFRSPNYVQPLLISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDDYEAMSFVCIVAILIYVAFFEIGPGPIPWFIVAELFSQGPRPAAIAVAGCCNWTSNFLVGMLFPSAAAYLGAYVFIIFAAFLIFFLIFTFFKVPETKGRTFEDIARAFEGQAHSGKGPAGVELNSMQPVKETPGNA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 43 | N-linked_Glycosylation | TILKDFLNYTLEERL HHHHHHHCCCHHHHH | 27.95 | 19349973 | |
| 216 | Ubiquitination | PRFLLINKKEEDQAT CCEEEEECCCHHHHH | 55.35 | - | |
| 217 | Ubiquitination | RFLLINKKEEDQATE CEEEEECCCHHHHHH | 62.94 | - | |
| 232 | Phosphorylation | ILQRLWGTSDVVQEI HHHHHHCCHHHHHHH | 15.35 | 22817900 | |
| 233 | Phosphorylation | LQRLWGTSDVVQEIQ HHHHHCCHHHHHHHH | 25.19 | 19060867 | |
| 243 | Ubiquitination | VQEIQEMKDESVRMS HHHHHHHCCHHHCCC | 58.55 | 22790023 | |
| 246 | Phosphorylation | IQEMKDESVRMSQEK HHHHCCHHHCCCHHH | 25.75 | 25338131 | |
| 250 | Phosphorylation | KDESVRMSQEKQVTV CCHHHCCCHHHHEEH | 25.32 | 25338131 | |
| 253 | Ubiquitination | SVRMSQEKQVTVLEL HHCCCHHHHEEHHHH | 42.29 | 22790023 | |
| 471 | Phosphorylation | AFEGQAHSGKGPAGV HHCCCCCCCCCCCCC | 45.26 | 27742792 | |
| 473 | Ubiquitination | EGQAHSGKGPAGVEL CCCCCCCCCCCCCEE | 65.81 | 22790023 | |
| 482 | Phosphorylation | PAGVELNSMQPVKET CCCCEECCCCCCCCC | 31.27 | 25266776 | |
| 487 | Ubiquitination | LNSMQPVKETPGNA- ECCCCCCCCCCCCC- | 63.65 | 22790023 | |
| 489 | Phosphorylation | SMQPVKETPGNA--- CCCCCCCCCCCC--- | 30.67 | 28066266 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GTR3_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GTR3_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GTR3_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of GTR3_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| N-linked Glycosylation | |
| Reference | PubMed |
| "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."; Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M.,Schiess R., Aebersold R., Watts J.D.; Nat. Biotechnol. 27:378-386(2009). Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-43, AND MASS SPECTROMETRY. | |
