| UniProt ID | GT251_MOUSE | |
|---|---|---|
| UniProt AC | Q8K297 | |
| Protein Name | Procollagen galactosyltransferase 1 | |
| Gene Name | Colgalt1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 617 | |
| Subcellular Localization | Endoplasmic reticulum lumen . Colocalized with PLOD3 and mannose binding lectin. | |
| Protein Description | Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen. By acting on collagen glycosylation, facilitates the formation of collagen triple helix.. | |
| Protein Sequence | MAALPRGSRGLPLLPLLLLLPPLGGPRGADGYFPEERWSPESPLQAPRVLIALLARNAAPALPATLGALEQLRHPRERTALWVATDHNTDNTSAILREWLVAVKGLYHSVEWRPAEEPSSYPDEEGPKHWSDSRYEHVMKLRQAALKSARDMWADYILFMDIDNLITNPDTLSLLIAENKTVVAPMLDSRAAYSNFWCGMTSQGYYKRTPAYIPIRKRDRRGCFAVPMVHSTFLIDLRKAASRNLAFYPTHPDYTWSFDDIIVFAFSCKQAEVQMYVCNKEVYGFLPVPLRAHSSLQDEAESFMHVQLEVMVKHPPVQLSRFISAPRKTSDKMGFDEVFMINLKRRRDRRERMLRALHEQEIDCQLVEAVDGKAMNTSQVEAMGIQMLPGYRDPYHGRPLTKGELGCFLSHYNIWKEVVDRGLQKSLVFEDDLRFEIFFKRRLMNLMRDVEREGLDWDLIYVGRKRMQVEHPEKAVPHVRNLVEADYSYWTLAYVISLQGAQKLLAAKPLAKMLPVDEFLPVMFDKHPMSEYKSHFSPRNLRAFSVEPLLIYPTHYTGDDGYVSDTETSVVWNNEQVKTDWDRAKSQKMREQQALSREAKNSDVLQSPLDSTARDEL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 91 | N-linked_Glycosylation | ATDHNTDNTSAILRE EECCCCCCHHHHHHH | 33.62 | 19349973 | |
| 179 | N-linked_Glycosylation | LSLLIAENKTVVAPM HHHHHCCCCEEEEEC | 35.95 | - | |
| 350 | Dimethylation | LKRRRDRRERMLRAL HHHHHHHHHHHHHHH | 39.91 | - | |
| 364 | S-nitrosocysteine | LHEQEIDCQLVEAVD HHHCCCCCEEEEEEC | 4.07 | - | |
| 364 | Glutathionylation | LHEQEIDCQLVEAVD HHHCCCCCEEEEEEC | 4.07 | 24333276 | |
| 364 | S-nitrosylation | LHEQEIDCQLVEAVD HHHCCCCCEEEEEEC | 4.07 | 20925432 | |
| 376 | N-linked_Glycosylation | AVDGKAMNTSQVEAM EECCCCCCHHHHHHH | 41.25 | - | |
| 607 | Phosphorylation | KNSDVLQSPLDSTAR HCCHHCCCCCCCCCH | 24.22 | 27742792 | |
| 611 | Phosphorylation | VLQSPLDSTARDEL- HCCCCCCCCCHHCC- | 31.48 | 27742792 | |
| 612 | Phosphorylation | LQSPLDSTARDEL-- CCCCCCCCCHHCC-- | 25.94 | 27742792 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GT251_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GT251_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GT251_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of GT251_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| N-linked Glycosylation | |
| Reference | PubMed |
| "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."; Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M.,Schiess R., Aebersold R., Watts J.D.; Nat. Biotechnol. 27:378-386(2009). Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-91, AND MASS SPECTROMETRY. | |
