GSTM7_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GSTM7_MOUSE
• UniProt AC: Q80W21
• Protein Name: Glutathione S-transferase Mu 7
• Gene Name: Gstm7
• Organism: Mus musculus (Mouse).
• Sequence Length: 218
• Subcellular Localization: Cytoplasm.
• Protein Description: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles..
• Protein Sequence: MPMTLGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNLPYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYNADFEKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFEAKCLDAFPNLKDFIARFEGLKKISDYMKTSRFLPRPMFTKMATWGSN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
31	Ubiquitination	TDSSYEEKRYTMGDA CCCCHHHHCCCCCCC	38.47	22790023
31	Acetylation	TDSSYEEKRYTMGDA CCCCHHHHCCCCCCC	38.47	23954790
34	Phosphorylation	SYEEKRYTMGDAPDY CHHHHCCCCCCCCCC	20.79	-
50	Acetylation	QSQWLNEKFKLGLDF HHHHHHHHHCCCCCC	46.88	66701763
52	Acetylation	QWLNEKFKLGLDFPN HHHHHHHCCCCCCCC	53.35	38024131
52	Ubiquitination	QWLNEKFKLGLDFPN HHHHHHHCCCCCCCC	53.35	-
62	Phosphorylation	LDFPNLPYLIDGSHK CCCCCCCEEECCCCC	21.32	23984901
67	Phosphorylation	LPYLIDGSHKITQSN CCEEECCCCCCCCHH	20.19	21082442
69	Acetylation	YLIDGSHKITQSNAI EEECCCCCCCCHHHH	49.50	66693039
69	Ubiquitination	YLIDGSHKITQSNAI EEECCCCCCCCHHHH	49.50	-
71	Phosphorylation	IDGSHKITQSNAILR ECCCCCCCCHHHHHH	30.65	23984901
73	Phosphorylation	GSHKITQSNAILRYL CCCCCCCHHHHHHHH	21.41	23984901
83	Ubiquitination	ILRYLGRKHNLCGET HHHHHCHHCCCCCCC	34.74	-
87	S-nitrosylation	LGRKHNLCGETEEER HCHHCCCCCCCHHHH	5.85	20925432
87	S-nitrosocysteine	LGRKHNLCGETEEER HCHHCCCCCCCHHHH	5.85	-
115	S-nitrosylation	RMVLARLCYNADFEK HHHHHHHHHCCCHHH	1.73	21278135
115	S-nitrosocysteine	RMVLARLCYNADFEK HHHHHHHHHCCCHHH	1.73	-
134	Ubiquitination	YLEQLPGMMRLYSEF HHHHCCHHHHHHHHH	1.02	27667366
139	Phosphorylation	PGMMRLYSEFLGKRP CHHHHHHHHHHCCCC	26.85	26643407
140	Ubiquitination	GMMRLYSEFLGKRPW HHHHHHHHHHCCCCC	31.19	27667366
144	Ubiquitination	LYSEFLGKRPWFAGD HHHHHHCCCCCCCCC	58.39	27667366
144	Acetylation	LYSEFLGKRPWFAGD HHHHHHCCCCCCCCC	58.39	25129601
151	Ubiquitination	KRPWFAGDKITFVDF CCCCCCCCCEEEEEE	35.44	27667366
174	S-nitrosylation	NQVFEAKCLDAFPNL CCHHHHHHHHCCCCH	5.54	21278135
174	S-nitrosocysteine	NQVFEAKCLDAFPNL CCHHHHHHHHCCCCH	5.54	-
192	Acetylation	IARFEGLKKISDYMK HHHHCHHHHHHHHHH	59.94	30204837

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GSTM7_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GSTM7_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GSTM7_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of GSTM7_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.