GSK31_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GSK31_SCHPO
• UniProt AC: Q9URT9
• Protein Name: Protein kinase gsk31
• Gene Name: gsk31
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 381
• Protein Sequence: MSDDSHLETKVVTDGTTGEKKTISYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKNRELQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPSEPNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTPSYHEISVMNPNYVNHSLPNVRPHTLESVMPHNCTKNAMDLLHKMLTYVPSKRISAIEVLTHPFFDELRDPNCMYHCSRDEGTIERHLPPLFNFNLAELSIRPNLNKAILPPHVYESLDVDINNFEPIVVKQADADS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSDDSHLET ------CCCCCCCEE	50.56	21712547
5	Phosphorylation	---MSDDSHLETKVV ---CCCCCCCEEEEE	34.66	21712547
121	Phosphorylation	WYTRRRKSIPNLSIK HHHCCCCCCCCCHHH	41.28	28889911
179	Phosphorylation	SAKVLVPSEPNVSYI CCEEECCCCCCHHHH	59.20	29996109
184	Phosphorylation	VPSEPNVSYICSRYY CCCCCCHHHHCCCCC	18.54	28889911
185	Phosphorylation	PSEPNVSYICSRYYR CCCCCHHHHCCCCCC	11.15	28889911
188	Phosphorylation	PNVSYICSRYYRAPE CCHHHHCCCCCCCCH	17.48	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GSK31_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GSK31_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GSK31_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of GSK31_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-184 AND TYR-185, ANDMASS SPECTROMETRY.
PubMed: 18257517