| UniProt ID | GSG1_HUMAN | |
|---|---|---|
| UniProt AC | Q2KHT4 | |
| Protein Name | Germ cell-specific gene 1 protein | |
| Gene Name | GSG1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 349 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein. Colocalizes with PAPOLB in the endoplasmic reticulum.. |
|
| Protein Description | May cause the redistribution of PAPOLB from the cytosol to the endoplasmic reticulum.. | |
| Protein Sequence | MAKMELSKAFSGQRTLLSAILSMLSLSFSTTSLLSNYWFVGTQKVPKPLCEKGLAAKCFDMPVSLDGDTNTSTQEVVQYNWETGDDRFSFRSFRSGMWLSCEETVEEPALLHPQSWKQFRALRSSGTAAAKGERCRSFIELTPPAKREILWLSLGTQITYIGLQFISFLLLLTDLLLTGNPACGLKLSAFAAVSSVLSGLLGMVAHMMYSQVFQATVNLGPEDWRPHVWNYGWAFYMAWLSFTCCMASAVTTFNTYTRMVLEFKCKHSKSFKENPNCLPHHHQCFPRRLSSAAPTVGPLTSYHQYHNQPIHSVSEGVDFYSELRNKGFQRGASQELKEAVRSSVEEEQC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 64 | Phosphorylation | KCFDMPVSLDGDTNT HHCCCCEEECCCCCC | 18.18 | 22210691 | |
| 89 | Phosphorylation | ETGDDRFSFRSFRSG CCCCCCEECEECCCC | 22.20 | 24719451 | |
| 124 | Phosphorylation | KQFRALRSSGTAAAK HHHHHHHHCCCHHHC | 33.69 | 23898821 | |
| 125 | Phosphorylation | QFRALRSSGTAAAKG HHHHHHHCCCHHHCC | 33.46 | 23898821 | |
| 137 | Phosphorylation | AKGERCRSFIELTPP HCCCCCHHHHHCCCC | 33.91 | 28348404 | |
| 142 | Phosphorylation | CRSFIELTPPAKREI CHHHHHCCCCHHHHH | 17.90 | 28348404 | |
| 155 (in isoform 4) | Phosphorylation | - | 16.52 | 30622161 | |
| 155 (in isoform 8) | Phosphorylation | - | 16.52 | 30622161 | |
| 158 (in isoform 4) | Phosphorylation | - | 2.95 | 30622161 | |
| 158 (in isoform 8) | Phosphorylation | - | 2.95 | 30622161 | |
| 190 (in isoform 8) | Phosphorylation | - | 3.94 | 28387310 | |
| 191 (in isoform 7) | Phosphorylation | - | 13.48 | 30622161 | |
| 194 (in isoform 7) | Phosphorylation | - | 15.25 | 30622161 | |
| 333 | Phosphorylation | KGFQRGASQELKEAV CCCCCCCCHHHHHHH | 27.32 | 30622161 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GSG1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GSG1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GSG1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ASAH1_HUMAN | ASAH1 | physical | 26186194 | |
| IL37_HUMAN | IL37 | physical | 26186194 | |
| IL37_HUMAN | IL37 | physical | 28514442 | |
| ASAH1_HUMAN | ASAH1 | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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