GSG1L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GSG1L_HUMAN
• UniProt AC: Q6UXU4
• Protein Name: Germ cell-specific gene 1-like protein
• Gene Name: GSG1L
• Organism: Homo sapiens (Human).
• Sequence Length: 331
• Subcellular Localization: Cell membrane; Multi-pass membrane protein. Cell junction, synapse.
• Protein Description: As a component of the inner core of AMPAR complex, modifies AMPA receptor (AMPAR) gating..
• Protein Sequence: MKTSRRGRALLAVALNLLALLFATTAFLTTHWCQGTQRVPKPGCGQGGRANCPNSGANATANGTAAPAAAAAAATASGNGPPGGALYSWETGDDRFLFRNFHTGIWYSCEEELSGLGEKCRSFIDLAPASEKGVLWLSVVSEVLYILLLVVGFSLMCLELFHSSNVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRKVFEQGYREEPTFIDPEAIKYFRERMEKRDGSEEDFHLDCRHERYPARHQPHMADSWPRSSAQEAPELNRQCWVLGHWV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
64	Phosphorylation	ANATANGTAAPAAAA CCCCCCCCHHHHHHH	21.32	-
244	Phosphorylation	TLNSYTKTVIEFRHK HHHHCCCEEEEHHHH	20.93	-
284	Phosphorylation	RMEKRDGSEEDFHLD HHHHCCCCCCCCCHH	41.94	25332170
297	Phosphorylation	LDCRHERYPARHQPH HHCCCCCCCCCCCCC	9.77	21214269
308	Phosphorylation	HQPHMADSWPRSSAQ CCCCCCCCCCCCCHH	29.46	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GSG1L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GSG1L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GSG1L_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of GSG1L_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.