GRXC5_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GRXC5_ARATH
• UniProt AC: Q8GWS0
• Protein Name: Glutaredoxin-C5, chloroplastic {ECO:0000303|PubMed:15170506}
• Gene Name: GRXC5 {ECO:0000303|PubMed:15170506}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 174
• Subcellular Localization: Plastid, chloroplast .
• Protein Description: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. Can assemble a [2Fe-2S] cluster, but cannot transfer it to an apoferredoxin..
• Protein Sequence: MAVTAFNTLKLVSSSLDPIPSVSCSSYSFSLIYVGSPYKRCLKQSCSVRAMTSSSSAASSSSSSFGSRMEESIRKTVTENTVVIYSKTWCSYCTEVKTLFKRLGVQPLVVELDQLGPQGPQLQKVLERLTGQHTVPNVFVCGKHIGGCTDTVKLNRKGDLELMLAEANGKNGQS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
52	Acetylation	SCSVRAMTSSSSAAS CCEEEEECCCCCCCC	25.19	22223895
90	Glutathionylation	VIYSKTWCSYCTEVK EEEECCCHHHHHHHH	2.22	21632542
148	Glutathionylation	CGKHIGGCTDTVKLN CCEECCCCCCCEEEC	2.34	21632542

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GRXC5_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GRXC5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GRXC5_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SUFE1_ARATH	CPSUFE	physical	24203231

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.