GRIN3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GRIN3_HUMAN
• UniProt AC: Q6ZVF9
• Protein Name: G protein-regulated inducer of neurite outgrowth 3
• Gene Name: GPRIN3
• Organism: Homo sapiens (Human).
• Sequence Length: 776
• Protein Description: May be involved in neurite outgrowth..
• Protein Sequence: MGTVPDPLRSAKTSLIAASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLTPGDKKKQLGADSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDAESLGIAIQNHLQRQIREHEKLIKTQNSQTRRSISSDTSSNKKLRGRQHSVFQSMLQNFRRPNCCVRPAPSSVLD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	TVPDPLRSAKTSLIA CCCCHHHHCHHHHHC	41.63	29759185
13	Phosphorylation	DPLRSAKTSLIAASG CHHHHCHHHHHCCCC	28.60	27080861
14	Phosphorylation	PLRSAKTSLIAASGK HHHHCHHHHHCCCCC	19.64	29759185
19	Phosphorylation	KTSLIAASGKEDDLG HHHHHCCCCCCCCCC	41.18	27080861
32	Phosphorylation	LGEPQAASPRHRPAL CCCCCCCCCCCCCEE	26.02	23401153
57	Phosphorylation	APAEPDLSPRAAAEA CCCCCCCCHHHHHHH	21.52	29255136
79	Phosphorylation	ETTQPDMSSPGVFNE CCCCCCCCCCCCCCC	40.54	27251275
80	Phosphorylation	TTQPDMSSPGVFNEV CCCCCCCCCCCCCCC	21.02	27251275
96	Phosphorylation	KAPATFNSPGNPQLP ECCCCCCCCCCCCCC	29.96	32142685
147	Phosphorylation	GDQPNAITSSMPEDS CCCCCCCCCCCCHHH	16.61	-
161	Phosphorylation	SLMRSQRTSNREQPE HHHHCCCCCCCCCCC	23.79	28348404
162	Phosphorylation	LMRSQRTSNREQPEK HHHCCCCCCCCCCCC	35.76	28348404
181	Phosphorylation	VGGVLSSSKDQVSCE CCCEECCCCCEEECC	36.55	32142685
191	Phosphorylation	QVSCEFPSPETIQGT EEECCCCCCCCCCCE	40.46	27080861
194	Phosphorylation	CEFPSPETIQGTVQT CCCCCCCCCCCEEEC	23.22	27080861
198	Phosphorylation	SPETIQGTVQTPVTA CCCCCCCEEECCCCE	7.96	27080861
201	Phosphorylation	TIQGTVQTPVTAARV CCCCEEECCCCEEEE	18.52	29255136
204	Phosphorylation	GTVQTPVTAARVVSH CEEECCCCEEEEEEC	18.79	27080861
210	Phosphorylation	VTAARVVSHSSSPVG CCEEEEEECCCCCCC	18.13	29255136
212	Phosphorylation	AARVVSHSSSPVGGP EEEEEECCCCCCCCC	25.63	29255136
213	Phosphorylation	ARVVSHSSSPVGGPE EEEEECCCCCCCCCC	32.98	29255136
214	Phosphorylation	RVVSHSSSPVGGPEG EEEECCCCCCCCCCC	26.98	29255136
299	Phosphorylation	MSRFKEASTMTNQAE HHHHHHHHHHHHHHH	21.58	23403867
300	Phosphorylation	SRFKEASTMTNQAES HHHHHHHHHHHHHHH	34.75	23403867
302	Phosphorylation	FKEASTMTNQAESEI HHHHHHHHHHHHHHH	25.03	23403867
332	Phosphorylation	VASVESRSVSTSPSI EEEEECCCCCCCHHH	29.69	26657352
334	Phosphorylation	SVESRSVSTSPSILT EEECCCCCCCHHHHH	25.14	29255136
335	Phosphorylation	VESRSVSTSPSILTA EECCCCCCCHHHHHH	42.37	29255136
336	Phosphorylation	ESRSVSTSPSILTAF ECCCCCCCHHHHHHH	14.78	29255136
338	Phosphorylation	RSVSTSPSILTAFLK CCCCCCHHHHHHHHH	29.96	29255136
341	Phosphorylation	STSPSILTAFLKESR CCCHHHHHHHHHHCC	17.44	29691806
345	Ubiquitination	SILTAFLKESRAPEH HHHHHHHHHCCCCCH	47.38	-
365	Phosphorylation	LRVICHSSGSHTLEL HEEEEECCCCEEEEE	22.20	-
420	Phosphorylation	LPGGVLKTSSINLVS CCCCEEECCEEEEEC	24.44	28857561
421	Phosphorylation	PGGVLKTSSINLVSS CCCEEECCEEEEECC	27.86	28857561
422	Phosphorylation	GGVLKTSSINLVSSN CCEEECCEEEEECCC	22.26	28857561
427	Phosphorylation	TSSINLVSSNAQHTC CCEEEEECCCCCEEE	22.50	28857561
433	Phosphorylation	VSSNAQHTCKEDGRL ECCCCCEEECCCCCC	17.13	28857561
481	Phosphorylation	SACSQAETSYGLGKF ECCCCCHHHCCCCCC	30.20	25884760
483	Phosphorylation	CSQAETSYGLGKFET CCCCHHHCCCCCCCC	24.64	-
493	Phosphorylation	GKFETRPSEFAEKTT CCCCCCHHHHHHHCC	41.89	30266825
512	Phosphorylation	TDPDCKLSDSCGSIS CCCCCCCCCCCCCCC	16.99	23312004
514	Phosphorylation	PDCKLSDSCGSISKA CCCCCCCCCCCCCCC	19.59	25849741
517	Phosphorylation	KLSDSCGSISKADHS CCCCCCCCCCCCCCC	28.19	25849741
519	Phosphorylation	SDSCGSISKADHSGS CCCCCCCCCCCCCCC	24.40	25850435
524	Phosphorylation	SISKADHSGSLDPTN CCCCCCCCCCCCCCC	30.53	29255136
526	Phosphorylation	SKADHSGSLDPTNKG CCCCCCCCCCCCCCC	32.39	29255136
542	Phosphorylation	AREKKPASPQVVKEK CCCCCCCCCCCEECC	25.13	26657352
547	Acetylation	PASPQVVKEKESTGT CCCCCCEECCCCCCC	65.30	30589061
571	Phosphorylation	LNPKSQESGGTESAA CCCCCCCCCCCCCCC	34.58	27486199
574	Phosphorylation	KSQESGGTESAANPT CCCCCCCCCCCCCCC	30.23	27486199
576	Phosphorylation	QESGGTESAANPTPS CCCCCCCCCCCCCCC	32.30	29255136
581	Phosphorylation	TESAANPTPSPIRKN CCCCCCCCCCCCCCC	35.88	29255136
583	Phosphorylation	SAANPTPSPIRKNQE CCCCCCCCCCCCCCC	35.12	29255136
606	Phosphorylation	TKTATSLSLPSDPMG CCCCCCCCCCCCCCC	37.69	27080861
609	Phosphorylation	ATSLSLPSDPMGDSS CCCCCCCCCCCCCCC	60.69	27080861
615	Phosphorylation	PSDPMGDSSPGSGKK CCCCCCCCCCCCCCC	32.47	23401153
616	Phosphorylation	SDPMGDSSPGSGKKT CCCCCCCCCCCCCCC	37.71	25850435
619	Phosphorylation	MGDSSPGSGKKTPSR CCCCCCCCCCCCCCC	51.31	25850435
622	Acetylation	SSPGSGKKTPSRSVK CCCCCCCCCCCCCCC	70.01	12432561
623	Phosphorylation	SPGSGKKTPSRSVKA CCCCCCCCCCCCCCC	29.95	32142685
625	Phosphorylation	GSGKKTPSRSVKASP CCCCCCCCCCCCCCC	42.28	23532336
627	Phosphorylation	GKKTPSRSVKASPRR CCCCCCCCCCCCCCC	32.10	29457462
631	Phosphorylation	PSRSVKASPRRPSRV CCCCCCCCCCCCHHH	17.14	25247763
636	Phosphorylation	KASPRRPSRVSEFLK CCCCCCCHHHHHHHH	43.43	27273156
639	Phosphorylation	PRRPSRVSEFLKEQK CCCCHHHHHHHHHCC	22.86	29978859
643	Ubiquitination	SRVSEFLKEQKLNVT HHHHHHHHHCCCCHH	64.52	33845483
659	Phosphorylation	AAAQVGLTPGDKKKQ HHHHCCCCCCCHHHH	21.21	29255136
671	Phosphorylation	KKQLGADSKLQLKQS HHHCCCCCCHHHHHC	34.43	28464451
672	Acetylation	KQLGADSKLQLKQSK HHCCCCCCHHHHHCC	40.58	20167786
676	Acetylation	ADSKLQLKQSKRVRD CCCCHHHHHCCCHHH	39.29	30589055
678	Phosphorylation	SKLQLKQSKRVRDVV CCHHHHHCCCHHHEE	22.35	28464451
734	Phosphorylation	QNSQTRRSISSDTSS CCHHHCHHCCCCCCC	24.43	26657352
737	Phosphorylation	QTRRSISSDTSSNKK HHCHHCCCCCCCCHH	43.15	23403867
740	Phosphorylation	RSISSDTSSNKKLRG HHCCCCCCCCHHHCC	36.58	33259812
743	Acetylation	SSDTSSNKKLRGRQH CCCCCCCHHHCCHHH	55.95	7480047
743	Ubiquitination	SSDTSSNKKLRGRQH CCCCCCCHHHCCHHH	55.95	33845483
751	Phosphorylation	KLRGRQHSVFQSMLQ HHCCHHHHHHHHHHH	19.11	26657352
755	Phosphorylation	RQHSVFQSMLQNFRR HHHHHHHHHHHHCCC	15.25	23312004

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GRIN3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GRIN3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GRIN3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of GRIN3_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.