GRAF_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GRAF_MOUSE
• UniProt AC: P08883
• Protein Name: Granzyme F
• Gene Name: Gzmf
• Organism: Mus musculus (Mouse).
• Sequence Length: 248
• Subcellular Localization: Cytoplasmic granule. Cytoplasmic granules of cytolytic T-lymphocytes.
• Protein Description: This enzyme is probably necessary for target cell lysis in cell-mediated immune responses..
• Protein Sequence: MPPILILLTLLLPLRAGAEEIIGGHEVKPHSRPYMARVRFVKDNGKRHSCGGFLVQDYFVLTAAHCTGSSMRVILGAHNIRAKEETQQIIPVAKAIPHPAYDDKDNTSDIMLLKLESKAKRTKAVRPLKLPRPNARVKPGHVCSVAGWGRTSINATQRSSCLREAQLIIQKDKECKKYFYKYFKTMQICAGDPKKIQSTYSGDSGGPLVCNNKAYGVLTYGLNRTIGPGVFTKVVHYLPWISRNMKLL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
46	Acetylation	RFVKDNGKRHSCGGF EEEEECCCEECCCCE	53.87	7844331
104	Acetylation	PHPAYDDKDNTSDIM CCCCCCCCCCCCCEE	50.40	6584703
106	N-linked_Glycosylation	PAYDDKDNTSDIMLL CCCCCCCCCCCEEEE	47.42	-
154	N-linked_Glycosylation	GWGRTSINATQRSSC CCCCCCCCHHHHHHH	36.38	-
223	N-linked_Glycosylation	GVLTYGLNRTIGPGV EEEEECCCCCCCCCH	34.39	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GRAF_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GRAF_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GRAF_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of GRAF_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.