GPR26_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GPR26_HUMAN
• UniProt AC: Q8NDV2
• Protein Name: G-protein coupled receptor 26
• Gene Name: GPR26
• Organism: Homo sapiens (Human).
• Sequence Length: 337
• Subcellular Localization: Cell membrane; Multi-pass membrane protein.
• Protein Description: Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP..
• Protein Sequence: MNSWDAGLAGLLVGTMGVSLLSNALVLLCLLHSADIRRQAPALFTLNLTCGNLLCTVVNMPLTLAGVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAALMVAYTWLHALTFPAAALALSWLGFHQLYASCTLCSRRPDERLRFAVFTGAFHALSFLLSFVVLCCTYLKVLKVARFHCKRIDVITMQTLVLLVDLHPSVRERCLEEQKRRRQRATKKISTFIGTFLVCFAPYVITRLVELFSTVPIGSHWGVLSKCLAYSKAASDPFVYSLLRHQYRKSCKEILNRLLHRRSIHSSGLTGDSHSQNILPVSE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
87	Phosphorylation	RLAAFLDTFLAANSM HHHHHHHHHHHHHHH	23.77	23612710
93	Phosphorylation	DTFLAANSMLSMAAL HHHHHHHHHHHHHHH	19.17	23612710
96	Phosphorylation	LAANSMLSMAALSID HHHHHHHHHHHHHCC	9.57	23612710
101	Phosphorylation	MLSMAALSIDRWVAV HHHHHHHHCCHHHHH	20.09	23612710

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GPR26_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GPR26_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GPR26_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of GPR26_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.