| UniProt ID | GPM6B_RAT | |
|---|---|---|
| UniProt AC | Q9JJK1 | |
| Protein Name | Neuronal membrane glycoprotein M6-b | |
| Gene Name | Gpm6b | |
| Organism | Rattus norvegicus (Rat). | |
| Sequence Length | 265 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein. Cell membrane . Colocalizes with SERT at the plasma membrane. |
|
| Protein Description | May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake.. | |
| Protein Sequence | MKPAMETAAEENTEQSQERKGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALAGTVAILEQHFSTNTSDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSPQSNGTSGVEQICVDVRQYGIIPWNAFPGKICGSALENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCPKF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 13 | Phosphorylation | ETAAEENTEQSQERK HHHHHHCHHHHHHHC | 38.39 | 27097102 | |
| 16 | Phosphorylation | AEENTEQSQERKGCF HHHCHHHHHHHCCHH | 27.98 | 27097102 | |
| 73 | N-linked_Glycosylation | LEQHFSTNTSDHALL HHHHCCCCCCCHHHH | 36.07 | - | |
| 177 | N-linked_Glycosylation | VIKSPQSNGTSGVEQ HHCCCCCCCCCCCEE | 53.14 | - | |
| 257 | Phosphorylation | YAVLKFKSREDCCPK CHHHHCCCHHHCCCC | 43.99 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GPM6B_RAT !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GPM6B_RAT !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GPM6B_RAT !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of GPM6B_RAT !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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